Synthesis and biological evaluation of curcumin analogues

Bukhari Syed Nasir Abbas, Ibrahim Jantan, Malina Jasamai, Waqas Ahmad, Muhammad Wahab Bin Amjad

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Among all the Curcuma species, Curcumin is the most studied curcuminoid. Curcumin is renowned for its plentiful biological and pharmacological activities. Synthesis of new curcumin analogues always gained attention by scientists in the area to solve the poor bioavailability problems associated with curcumin. Uncountable analogues of curcumin have synthesized in past decades. In this review, alterations in the fundamental structure of curcumin to access associated compounds by chemical synthesis are described. We have endeavoured to sum up the biological activities of only synthetic analogues of curcumin and also most popular types of synthetic analogues of curcumin. This overview of synthetic data will provide an ease for the future scientists to develop new synthetic strategies for curcumin analogues as well as it shows the pharmacological importance and need of novel analogues.

Original languageEnglish
Pages (from-to)501-513
Number of pages13
JournalJournal of Medical Sciences (Faisalabad)
Volume13
Issue number7
DOIs
Publication statusPublished - 2013

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Curcumin
Pharmacology
Curcuma
Biological Availability

Keywords

  • Anti-inflammato~y
  • Anticancer
  • Antioxidant
  • Curcumin
  • Synthetic analogues

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Synthesis and biological evaluation of curcumin analogues. / Syed Nasir Abbas, Bukhari; Jantan, Ibrahim; Jasamai, Malina; Ahmad, Waqas; Amjad, Muhammad Wahab Bin.

In: Journal of Medical Sciences (Faisalabad), Vol. 13, No. 7, 2013, p. 501-513.

Research output: Contribution to journalArticle

Syed Nasir Abbas, Bukhari ; Jantan, Ibrahim ; Jasamai, Malina ; Ahmad, Waqas ; Amjad, Muhammad Wahab Bin. / Synthesis and biological evaluation of curcumin analogues. In: Journal of Medical Sciences (Faisalabad). 2013 ; Vol. 13, No. 7. pp. 501-513.
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