Synthesis and antibacterial evaluation of some novel imidazole and benzimidazole sulfonamides

Nassir N. Al-Mohammed, Yatimah Alias, Zanariah Abdullah, Raied M. Shakir, Ekhlass M. Taha, Aidil Abdul Hamid

Research output: Contribution to journalArticle

39 Citations (Scopus)

Abstract

Several new substituted sulfonamide compounds were synthesized and their structures were confirmed by 1H-NMR, 13C-NMR, FT-IR, and mass spectroscopy. The antibacterial activities of the synthesized compounds were screened against standard strains of six Gram positive and four Gram negative bacteria using the microbroth dilution assay. Most of the compounds studied showed promising activities against both types of bacteria.

Original languageEnglish
Pages (from-to)11978-11995
Number of pages18
JournalMolecules
Volume18
Issue number10
DOIs
Publication statusPublished - Oct 2013

Fingerprint

Sulfonamides
Gram-Negative Bacteria
imidazoles
bacteria
Mass Spectrometry
Bacteria
Nuclear magnetic resonance
nuclear magnetic resonance
evaluation
synthesis
Dilution
dilution
Assays
mass spectroscopy
Spectroscopy
Carbon-13 Magnetic Resonance Spectroscopy
benzimidazole
Proton Magnetic Resonance Spectroscopy
imidazole

Keywords

  • 4-methoxybenzenesulfonamide
  • 4-methylbenzenesulfonamide
  • 4-nitrobenzenesulfonamide
  • Antibacterial activity
  • Benzimidazole
  • Imidazole
  • Sulfonamide

ASJC Scopus subject areas

  • Organic Chemistry
  • Medicine(all)

Cite this

Synthesis and antibacterial evaluation of some novel imidazole and benzimidazole sulfonamides. / Al-Mohammed, Nassir N.; Alias, Yatimah; Abdullah, Zanariah; Shakir, Raied M.; Taha, Ekhlass M.; Abdul Hamid, Aidil.

In: Molecules, Vol. 18, No. 10, 10.2013, p. 11978-11995.

Research output: Contribution to journalArticle

Al-Mohammed, Nassir N. ; Alias, Yatimah ; Abdullah, Zanariah ; Shakir, Raied M. ; Taha, Ekhlass M. ; Abdul Hamid, Aidil. / Synthesis and antibacterial evaluation of some novel imidazole and benzimidazole sulfonamides. In: Molecules. 2013 ; Vol. 18, No. 10. pp. 11978-11995.
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