Syndrome of inappropriate antidiuretic hormone caused by continuous lumbar spinal fluid drainage after transphenoidal surgery

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

A 53-year-old acromegalic woman had cerebrospinal fluid rhinorrhoea following transphenoidal surgery for a pituitary microadenoma. A continuous lumbar spinal fluid drainage catheter was inserted and on the sixth postoperative day, she developed hyponatremia with features of syndrome of inappropriate antidiuretic hormone (SIADH) requiring hypertonic saline administration. Over-drainage is potentially hazardous and close biochemical monitoring is required. To our knowledge, this is the first reported case of SIADH caused by continuous lumbar drainage in an adult.

Original languageEnglish
Pages (from-to)75-76
Number of pages2
JournalSingapore Medical Journal
Volume47
Issue number1
Publication statusPublished - Jan 2006

Fingerprint

Vasopressins
Drainage
Cerebrospinal Fluid Rhinorrhea
Hyponatremia
Catheters

Keywords

  • Cerebrospinal fluid rhinorrhoea
  • Continuous lumbar spinal fluid drainage
  • Hyponatremia
  • Syndrome of inappropriate antidiuretic hormone (SIADH)
  • Transphenoid surgery

ASJC Scopus subject areas

  • Medicine(all)

Cite this

@article{fa7764204faf401c8a3a954a2e8bfac2,
title = "Syndrome of inappropriate antidiuretic hormone caused by continuous lumbar spinal fluid drainage after transphenoidal surgery",
abstract = "A 53-year-old acromegalic woman had cerebrospinal fluid rhinorrhoea following transphenoidal surgery for a pituitary microadenoma. A continuous lumbar spinal fluid drainage catheter was inserted and on the sixth postoperative day, she developed hyponatremia with features of syndrome of inappropriate antidiuretic hormone (SIADH) requiring hypertonic saline administration. Over-drainage is potentially hazardous and close biochemical monitoring is required. To our knowledge, this is the first reported case of SIADH caused by continuous lumbar drainage in an adult.",
keywords = "Cerebrospinal fluid rhinorrhoea, Continuous lumbar spinal fluid drainage, Hyponatremia, Syndrome of inappropriate antidiuretic hormone (SIADH), Transphenoid surgery",
author = "Norlela Sukor and Kamaruddin, {Nor Azmi} and Khalid, {B. A K}",
year = "2006",
month = "1",
language = "English",
volume = "47",
pages = "75--76",
journal = "Singapore Medical Journal",
issn = "0037-5675",
publisher = "Singapore Medical Association",
number = "1",

}

TY - JOUR

T1 - Syndrome of inappropriate antidiuretic hormone caused by continuous lumbar spinal fluid drainage after transphenoidal surgery

AU - Sukor, Norlela

AU - Kamaruddin, Nor Azmi

AU - Khalid, B. A K

PY - 2006/1

Y1 - 2006/1

N2 - A 53-year-old acromegalic woman had cerebrospinal fluid rhinorrhoea following transphenoidal surgery for a pituitary microadenoma. A continuous lumbar spinal fluid drainage catheter was inserted and on the sixth postoperative day, she developed hyponatremia with features of syndrome of inappropriate antidiuretic hormone (SIADH) requiring hypertonic saline administration. Over-drainage is potentially hazardous and close biochemical monitoring is required. To our knowledge, this is the first reported case of SIADH caused by continuous lumbar drainage in an adult.

AB - A 53-year-old acromegalic woman had cerebrospinal fluid rhinorrhoea following transphenoidal surgery for a pituitary microadenoma. A continuous lumbar spinal fluid drainage catheter was inserted and on the sixth postoperative day, she developed hyponatremia with features of syndrome of inappropriate antidiuretic hormone (SIADH) requiring hypertonic saline administration. Over-drainage is potentially hazardous and close biochemical monitoring is required. To our knowledge, this is the first reported case of SIADH caused by continuous lumbar drainage in an adult.

KW - Cerebrospinal fluid rhinorrhoea

KW - Continuous lumbar spinal fluid drainage

KW - Hyponatremia

KW - Syndrome of inappropriate antidiuretic hormone (SIADH)

KW - Transphenoid surgery

UR - http://www.scopus.com/inward/record.url?scp=30544447579&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=30544447579&partnerID=8YFLogxK

M3 - Article

C2 - 16397727

AN - SCOPUS:30544447579

VL - 47

SP - 75

EP - 76

JO - Singapore Medical Journal

JF - Singapore Medical Journal

SN - 0037-5675

IS - 1

ER -