Pengembungan hidrogel selulosa bakteria-asid akrilik

Sensitiviti terhadap rangsangan luar

Translated title of the contribution: Swelling of bacterial cellulose-acrylic acid hydrogels: sensitivity towards external stimuli

Nadia Halib, Mohd Cairul Iqbal Mohd Amin, Ishak Ahmad, Zulkifu Mohamed Hashim, Noriah Jamal

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

This study evaluated various environmental factors affecting the swelling degree of bacterial cellulose-acrylic acid hydrogels. Aqueous bacterial cellulose-acrylic acid (4:1) mixtures were prepared and subjected to electron beam irradiation at 30 and 50 kGy. Swelling rate under influenced ofpH, temperature and ionic strength was investigated from 1 to 24 hours. Swelling degree of hydrogels was dependent on irradiation dose: those synthesized at 50 kGy exhibited significant higher swelling degree (p<0.0001) in methanol (619%) compared to water (510%) at room temperature after 24 hours. External ionic strength affected swelling, i.e, elevation in sodium chloride concentration decreased swelling degree. Hydrogels were also sensitive to pH: swelling increased with increasing pH and was optimal at pH 7. Swelling also increased with increasing temperature from 25°C to 50°C. In conclusion, the ability of electron irradiated bacterial cellulose-acrylic acid hydrogels to respond to various external environment make it a material to be developed as an active delivery system for drugs, proteins and hormones.

Original languageUndefined/Unknown
Pages (from-to)785-791
Number of pages7
JournalSains Malaysiana
Volume38
Issue number5
Publication statusPublished - Oct 2009

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Hydrogels
Cellulose
Osmolar Concentration
Temperature
Electrons
Drug Delivery Systems
Sodium Chloride
Methanol
Hormones
acrylic acid
Water
Proteins

Keywords

  • Bacterial cellulose
  • Delivery systems
  • External stimuli
  • Hydrogels

ASJC Scopus subject areas

  • General

Cite this

Pengembungan hidrogel selulosa bakteria-asid akrilik : Sensitiviti terhadap rangsangan luar. / Halib, Nadia; Mohd Amin, Mohd Cairul Iqbal; Ahmad, Ishak; Hashim, Zulkifu Mohamed; Jamal, Noriah.

In: Sains Malaysiana, Vol. 38, No. 5, 10.2009, p. 785-791.

Research output: Contribution to journalArticle

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