Superparamagnetic calcium ferrite nanoparticles synthesized using a simple sol-gel method for targeted drug delivery

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

The calcium ferrite nano-particles (CaFe2O4 NPs) were synthesized using a sol-gel method for targeted drug delivery application. The proposed nano-particles were initially prepared by mixing calcium and iron nitrates that were added with citric acid in order to prevent agglomeration and subsequently calcined at a temperature of 550°C to obtain small particle size. The prepared nanoparticles were characterized by using an XRD (X-ray diffraction), which revealed the configuration of orthorhombic structures of the CaFe2O4 nano-particles. A crystallite size of ~13.59 nm was obtained using a Scherer's formula. Magnetic analysis using a VSM (Vibrating Sample Magnetometer analysis), revealed that the synthesized particles exhibited super-paramagnetic behavior having magnetization saturation of approximately 88.3emu/g. Detailed observation via the scanning electron microscopy (SEM) showed the calcium ferrite nano-particles were spherical in shape.

Original languageEnglish
Pages (from-to)S103-S110
JournalBio-Medical Materials and Engineering
Volume26
DOIs
Publication statusPublished - 2015

Fingerprint

Polymethyl Methacrylate
Nanoparticles
Sol-gel process
Ferrite
Calcium
Gels
Particle Size
Citric Acid
X-Ray Diffraction
Pharmaceutical Preparations
Electron Scanning Microscopy
Iron
Citric acid
Observation
Magnetometers
Saturation magnetization
Crystallite size
Nitrates
Temperature
Agglomeration

Keywords

  • drug delivery
  • Magnetic nanoparticles
  • superparamagnetic

ASJC Scopus subject areas

  • Medicine(all)

Cite this

@article{b0d27838eb504bd38e53fc70be996dbd,
title = "Superparamagnetic calcium ferrite nanoparticles synthesized using a simple sol-gel method for targeted drug delivery",
abstract = "The calcium ferrite nano-particles (CaFe2O4 NPs) were synthesized using a sol-gel method for targeted drug delivery application. The proposed nano-particles were initially prepared by mixing calcium and iron nitrates that were added with citric acid in order to prevent agglomeration and subsequently calcined at a temperature of 550°C to obtain small particle size. The prepared nanoparticles were characterized by using an XRD (X-ray diffraction), which revealed the configuration of orthorhombic structures of the CaFe2O4 nano-particles. A crystallite size of ~13.59 nm was obtained using a Scherer's formula. Magnetic analysis using a VSM (Vibrating Sample Magnetometer analysis), revealed that the synthesized particles exhibited super-paramagnetic behavior having magnetization saturation of approximately 88.3emu/g. Detailed observation via the scanning electron microscopy (SEM) showed the calcium ferrite nano-particles were spherical in shape.",
keywords = "drug delivery, Magnetic nanoparticles, superparamagnetic",
author = "Sulaiman, {N. H.} and Ghazali, {Mariyam Jameelah} and {Yeop Majlis}, Burhanuddin and Jumril Yunas and Masfueh Razali",
year = "2015",
doi = "10.3233/BME-151295",
language = "English",
volume = "26",
pages = "S103--S110",
journal = "Bio-Medical Materials and Engineering",
issn = "0959-2989",
publisher = "IOS Press",

}

TY - JOUR

T1 - Superparamagnetic calcium ferrite nanoparticles synthesized using a simple sol-gel method for targeted drug delivery

AU - Sulaiman, N. H.

AU - Ghazali, Mariyam Jameelah

AU - Yeop Majlis, Burhanuddin

AU - Yunas, Jumril

AU - Razali, Masfueh

PY - 2015

Y1 - 2015

N2 - The calcium ferrite nano-particles (CaFe2O4 NPs) were synthesized using a sol-gel method for targeted drug delivery application. The proposed nano-particles were initially prepared by mixing calcium and iron nitrates that were added with citric acid in order to prevent agglomeration and subsequently calcined at a temperature of 550°C to obtain small particle size. The prepared nanoparticles were characterized by using an XRD (X-ray diffraction), which revealed the configuration of orthorhombic structures of the CaFe2O4 nano-particles. A crystallite size of ~13.59 nm was obtained using a Scherer's formula. Magnetic analysis using a VSM (Vibrating Sample Magnetometer analysis), revealed that the synthesized particles exhibited super-paramagnetic behavior having magnetization saturation of approximately 88.3emu/g. Detailed observation via the scanning electron microscopy (SEM) showed the calcium ferrite nano-particles were spherical in shape.

AB - The calcium ferrite nano-particles (CaFe2O4 NPs) were synthesized using a sol-gel method for targeted drug delivery application. The proposed nano-particles were initially prepared by mixing calcium and iron nitrates that were added with citric acid in order to prevent agglomeration and subsequently calcined at a temperature of 550°C to obtain small particle size. The prepared nanoparticles were characterized by using an XRD (X-ray diffraction), which revealed the configuration of orthorhombic structures of the CaFe2O4 nano-particles. A crystallite size of ~13.59 nm was obtained using a Scherer's formula. Magnetic analysis using a VSM (Vibrating Sample Magnetometer analysis), revealed that the synthesized particles exhibited super-paramagnetic behavior having magnetization saturation of approximately 88.3emu/g. Detailed observation via the scanning electron microscopy (SEM) showed the calcium ferrite nano-particles were spherical in shape.

KW - drug delivery

KW - Magnetic nanoparticles

KW - superparamagnetic

UR - http://www.scopus.com/inward/record.url?scp=84978906421&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84978906421&partnerID=8YFLogxK

U2 - 10.3233/BME-151295

DO - 10.3233/BME-151295

M3 - Article

VL - 26

SP - S103-S110

JO - Bio-Medical Materials and Engineering

JF - Bio-Medical Materials and Engineering

SN - 0959-2989

ER -