Superficial siderosis of the central nervous system following cervical nerve root avulsion

the importance of early diagnosis and surgery.

K. Aquilina, Ramesh Kumar Athi Kumar, J. Lu, D. Rawluk

Research output: Contribution to journalReview article

30 Citations (Scopus)

Abstract

Superficial siderosis (SS) of the central nervous system is an insidious, progressive, irreversible and debilitating neurological disorder caused by recurrent haemorrhage within the subarachnoid space. The subsequent deposition of haemorrhagic breakdown products in the spinal cord and nervous tissues leads to the loss of neurones and myelin, and to the development of a neurological deficit. In a small number of patients, the source of haemorrhage is related to traumatic cervical nerve root avulsion occurring several years prior to the onset of symptoms. Surgical ablation of the source has been shown to halt the progression of the disease, at least in the short term. We review the literature on SS secondary to cervical nerve root avulsion and report a further case in which surgical management was successful in halting disease progression. We emphasize that early detection and recognition of the initial non-progressive symptoms related to this poorly known disease, coupled with timely surgical management, minimizes the degree of neurological disability.

Original languageEnglish
JournalActa Neurochirurgica
Volume147
Issue number3
Publication statusPublished - Mar 2005
Externally publishedYes

Fingerprint

Siderosis
Radiculopathy
Disease Progression
Early Diagnosis
Central Nervous System
Hemorrhage
Nerve Tissue
Subarachnoid Space
Myelin Sheath
Nervous System Diseases
Spinal Cord
Neurons

ASJC Scopus subject areas

  • Clinical Neurology
  • Surgery

Cite this

Superficial siderosis of the central nervous system following cervical nerve root avulsion : the importance of early diagnosis and surgery. / Aquilina, K.; Athi Kumar, Ramesh Kumar; Lu, J.; Rawluk, D.

In: Acta Neurochirurgica, Vol. 147, No. 3, 03.2005.

Research output: Contribution to journalReview article

@article{10d33ef652ea44acb4213773a64e93f2,
title = "Superficial siderosis of the central nervous system following cervical nerve root avulsion: the importance of early diagnosis and surgery.",
abstract = "Superficial siderosis (SS) of the central nervous system is an insidious, progressive, irreversible and debilitating neurological disorder caused by recurrent haemorrhage within the subarachnoid space. The subsequent deposition of haemorrhagic breakdown products in the spinal cord and nervous tissues leads to the loss of neurones and myelin, and to the development of a neurological deficit. In a small number of patients, the source of haemorrhage is related to traumatic cervical nerve root avulsion occurring several years prior to the onset of symptoms. Surgical ablation of the source has been shown to halt the progression of the disease, at least in the short term. We review the literature on SS secondary to cervical nerve root avulsion and report a further case in which surgical management was successful in halting disease progression. We emphasize that early detection and recognition of the initial non-progressive symptoms related to this poorly known disease, coupled with timely surgical management, minimizes the degree of neurological disability.",
author = "K. Aquilina and {Athi Kumar}, {Ramesh Kumar} and J. Lu and D. Rawluk",
year = "2005",
month = "3",
language = "English",
volume = "147",
journal = "Acta Neurochirurgica",
issn = "0001-6268",
publisher = "Springer Wien",
number = "3",

}

TY - JOUR

T1 - Superficial siderosis of the central nervous system following cervical nerve root avulsion

T2 - the importance of early diagnosis and surgery.

AU - Aquilina, K.

AU - Athi Kumar, Ramesh Kumar

AU - Lu, J.

AU - Rawluk, D.

PY - 2005/3

Y1 - 2005/3

N2 - Superficial siderosis (SS) of the central nervous system is an insidious, progressive, irreversible and debilitating neurological disorder caused by recurrent haemorrhage within the subarachnoid space. The subsequent deposition of haemorrhagic breakdown products in the spinal cord and nervous tissues leads to the loss of neurones and myelin, and to the development of a neurological deficit. In a small number of patients, the source of haemorrhage is related to traumatic cervical nerve root avulsion occurring several years prior to the onset of symptoms. Surgical ablation of the source has been shown to halt the progression of the disease, at least in the short term. We review the literature on SS secondary to cervical nerve root avulsion and report a further case in which surgical management was successful in halting disease progression. We emphasize that early detection and recognition of the initial non-progressive symptoms related to this poorly known disease, coupled with timely surgical management, minimizes the degree of neurological disability.

AB - Superficial siderosis (SS) of the central nervous system is an insidious, progressive, irreversible and debilitating neurological disorder caused by recurrent haemorrhage within the subarachnoid space. The subsequent deposition of haemorrhagic breakdown products in the spinal cord and nervous tissues leads to the loss of neurones and myelin, and to the development of a neurological deficit. In a small number of patients, the source of haemorrhage is related to traumatic cervical nerve root avulsion occurring several years prior to the onset of symptoms. Surgical ablation of the source has been shown to halt the progression of the disease, at least in the short term. We review the literature on SS secondary to cervical nerve root avulsion and report a further case in which surgical management was successful in halting disease progression. We emphasize that early detection and recognition of the initial non-progressive symptoms related to this poorly known disease, coupled with timely surgical management, minimizes the degree of neurological disability.

UR - http://www.scopus.com/inward/record.url?scp=23044475069&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=23044475069&partnerID=8YFLogxK

M3 - Review article

VL - 147

JO - Acta Neurochirurgica

JF - Acta Neurochirurgica

SN - 0001-6268

IS - 3

ER -