Study of Electrical Impedance Tomography as a primary screening technique for breast cancer

N. M. Zain, Kanaga Kumari Chelliah, Sharifah Majedah Idrus Alhabshi, Suraya Aziz, Nani Harlina Md. Latar

Research output: Chapter in Book/Report/Conference proceedingConference contribution

4 Citations (Scopus)

Abstract

Electrical Impedance Tomography (EIT) is a potential adjunct modality for breast cancer screening. It is mobile and does not use ionizing radiation. It is based on the theory that cancer cells display altered local dielectric properties, thus illustrate measurably higher conductivity values. EIT was validated with mammography (MMG); ultrasound (US) and biopsy. A total of 150 symptomatic mammography patients with US breast above 40 years undergone EIT. Respondents were chosen using convenience sampling. The analysis of MMG, US and EIT were done independently by four independent radiologists with minimum of five years' experience with BI-RADS classification for recognition of abnormalities. A total of 62 (41.3%) subjects had consistent interpretation of EIT, MMG and US whilst 88 (58.7%) subjects had coherent interpretation. Intra-rater agreement for EIT, MMG and US interpretation was good (κ≥0.7). EIT had 64.4% of sensitivity using diagnostic MMG, 70.1% of specificity, 67.1% of positive and 67.5% of negative predictive value. Specificity and positive predictive value increased to 76.3% and 80%, respectively when combination EIT, MMG and US were used. From 13 biopsy cases; 90% was proven as malignant lesions whilst 76.9% of 10 biopsy cases as benign lesions by EIT. Menopausal status and age (p>0.05) was not correlated significantly with EIT performance. EIT had 64.4% of sensitivity and is recommended to be a potential primary screening technique for detection of breast abnormality prior Breast Self Examination However MMG has to be done to confirm the diagnosis.

Original languageEnglish
Title of host publicationIECBES 2014, Conference Proceedings - 2014 IEEE Conference on Biomedical Engineering and Sciences: "Miri, Where Engineering in Medicine and Biology and Humanity Meet"
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages220-224
Number of pages5
ISBN (Print)9781479940844
DOIs
Publication statusPublished - 23 Feb 2015
Event3rd IEEE Conference on Biomedical Engineering and Sciences, IECBES 2014 - Kuala Lumpur
Duration: 8 Dec 201410 Dec 2014

Other

Other3rd IEEE Conference on Biomedical Engineering and Sciences, IECBES 2014
CityKuala Lumpur
Period8/12/1410/12/14

Fingerprint

Acoustic impedance
Tomography
Mammography
Screening
Ultrasonics
Biopsy
Ionizing radiation
Dielectric properties
Cells
Sampling

ASJC Scopus subject areas

  • Biomedical Engineering

Cite this

Zain, N. M., Chelliah, K. K., Idrus Alhabshi, S. M., Aziz, S., & Md. Latar, N. H. (2015). Study of Electrical Impedance Tomography as a primary screening technique for breast cancer. In IECBES 2014, Conference Proceedings - 2014 IEEE Conference on Biomedical Engineering and Sciences: "Miri, Where Engineering in Medicine and Biology and Humanity Meet" (pp. 220-224). [7047490] Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/IECBES.2014.7047490

Study of Electrical Impedance Tomography as a primary screening technique for breast cancer. / Zain, N. M.; Chelliah, Kanaga Kumari; Idrus Alhabshi, Sharifah Majedah; Aziz, Suraya; Md. Latar, Nani Harlina.

IECBES 2014, Conference Proceedings - 2014 IEEE Conference on Biomedical Engineering and Sciences: "Miri, Where Engineering in Medicine and Biology and Humanity Meet". Institute of Electrical and Electronics Engineers Inc., 2015. p. 220-224 7047490.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Zain, NM, Chelliah, KK, Idrus Alhabshi, SM, Aziz, S & Md. Latar, NH 2015, Study of Electrical Impedance Tomography as a primary screening technique for breast cancer. in IECBES 2014, Conference Proceedings - 2014 IEEE Conference on Biomedical Engineering and Sciences: "Miri, Where Engineering in Medicine and Biology and Humanity Meet"., 7047490, Institute of Electrical and Electronics Engineers Inc., pp. 220-224, 3rd IEEE Conference on Biomedical Engineering and Sciences, IECBES 2014, Kuala Lumpur, 8/12/14. https://doi.org/10.1109/IECBES.2014.7047490
Zain NM, Chelliah KK, Idrus Alhabshi SM, Aziz S, Md. Latar NH. Study of Electrical Impedance Tomography as a primary screening technique for breast cancer. In IECBES 2014, Conference Proceedings - 2014 IEEE Conference on Biomedical Engineering and Sciences: "Miri, Where Engineering in Medicine and Biology and Humanity Meet". Institute of Electrical and Electronics Engineers Inc. 2015. p. 220-224. 7047490 https://doi.org/10.1109/IECBES.2014.7047490
Zain, N. M. ; Chelliah, Kanaga Kumari ; Idrus Alhabshi, Sharifah Majedah ; Aziz, Suraya ; Md. Latar, Nani Harlina. / Study of Electrical Impedance Tomography as a primary screening technique for breast cancer. IECBES 2014, Conference Proceedings - 2014 IEEE Conference on Biomedical Engineering and Sciences: "Miri, Where Engineering in Medicine and Biology and Humanity Meet". Institute of Electrical and Electronics Engineers Inc., 2015. pp. 220-224
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