Structure revision of mitragynaline, an indole alkaloid in Mitragyna speciosa

Hiromitsu Takayama, Hayato Ishikawa, Mika Kurihara, Mariko Kitajima, Shin Ichiro Sakai, Norio Aimi, Hiroko Seki, Kentaro Yamaguchi, Ikram M. Said, Peter J. Houghton

    Research output: Contribution to journalArticle

    19 Citations (Scopus)

    Abstract

    The structure of mitragynaline, an indole alkaloid isolated from Malaysian Mitragyna speciosa, was revised as formula 3 by analysis of the NMR spectra measured at low temperature and by chemical transformation with DDQ oxidation from the known alkaloid mitragynine (5).

    Original languageEnglish
    Pages (from-to)1741-1743
    Number of pages3
    JournalTetrahedron Letters
    Volume42
    Issue number9
    DOIs
    Publication statusPublished - 26 Feb 2001

    Fingerprint

    Mitragyna
    Indole Alkaloids
    Alkaloids
    Spectrum Analysis
    Nuclear magnetic resonance
    Oxidation
    Temperature
    mitragynine

    Keywords

    • Alkaloids
    • Indoles
    • NMR
    • Oxidation

    ASJC Scopus subject areas

    • Biochemistry
    • Organic Chemistry
    • Drug Discovery

    Cite this

    Takayama, H., Ishikawa, H., Kurihara, M., Kitajima, M., Sakai, S. I., Aimi, N., ... Houghton, P. J. (2001). Structure revision of mitragynaline, an indole alkaloid in Mitragyna speciosa. Tetrahedron Letters, 42(9), 1741-1743. https://doi.org/10.1016/S0040-4039(01)00006-5

    Structure revision of mitragynaline, an indole alkaloid in Mitragyna speciosa. / Takayama, Hiromitsu; Ishikawa, Hayato; Kurihara, Mika; Kitajima, Mariko; Sakai, Shin Ichiro; Aimi, Norio; Seki, Hiroko; Yamaguchi, Kentaro; Said, Ikram M.; Houghton, Peter J.

    In: Tetrahedron Letters, Vol. 42, No. 9, 26.02.2001, p. 1741-1743.

    Research output: Contribution to journalArticle

    Takayama, H, Ishikawa, H, Kurihara, M, Kitajima, M, Sakai, SI, Aimi, N, Seki, H, Yamaguchi, K, Said, IM & Houghton, PJ 2001, 'Structure revision of mitragynaline, an indole alkaloid in Mitragyna speciosa', Tetrahedron Letters, vol. 42, no. 9, pp. 1741-1743. https://doi.org/10.1016/S0040-4039(01)00006-5
    Takayama H, Ishikawa H, Kurihara M, Kitajima M, Sakai SI, Aimi N et al. Structure revision of mitragynaline, an indole alkaloid in Mitragyna speciosa. Tetrahedron Letters. 2001 Feb 26;42(9):1741-1743. https://doi.org/10.1016/S0040-4039(01)00006-5
    Takayama, Hiromitsu ; Ishikawa, Hayato ; Kurihara, Mika ; Kitajima, Mariko ; Sakai, Shin Ichiro ; Aimi, Norio ; Seki, Hiroko ; Yamaguchi, Kentaro ; Said, Ikram M. ; Houghton, Peter J. / Structure revision of mitragynaline, an indole alkaloid in Mitragyna speciosa. In: Tetrahedron Letters. 2001 ; Vol. 42, No. 9. pp. 1741-1743.
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    AU - Sakai, Shin Ichiro

    AU - Aimi, Norio

    AU - Seki, Hiroko

    AU - Yamaguchi, Kentaro

    AU - Said, Ikram M.

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