Spontaneous conception following GnRHa and progestogen therapy in adenomyosis

Research output: Contribution to journalReview article

1 Citation (Scopus)

Abstract

Adenomyosis is a common gynaecological disorder that is associated with infertility and miscarriage. We report a case of adenomyosis presented with urinary retention and infertility. The patient successfully conceived spontaneously following GnRHa followed by progestogen therapy. This treatment option might provide a synergistic effect in improving fertility and pregnancy outcome for women with adenomyosis. This modality has no potential surgical risk; it minimises the long-term side effects of GnRHa and also provides luteal support.

Original languageEnglish
Pages (from-to)77-79
Number of pages3
JournalHormone Molecular Biology and Clinical Investigation
Volume27
Issue number2
DOIs
Publication statusPublished - 1 Aug 2016

Fingerprint

Adenomyosis
Progestins
Infertility
Urinary Retention
Corpus Luteum
Spontaneous Abortion
Pregnancy Outcome
Fertility
Therapeutics

Keywords

  • adenomyosis
  • dydrogesterone
  • gonadotropin releasing hormone agonist
  • infertility
  • progestogen

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Medicine(all)
  • Molecular Biology
  • Endocrinology

Cite this

@article{b8de315f265d4187b8617efaa9269a79,
title = "Spontaneous conception following GnRHa and progestogen therapy in adenomyosis",
abstract = "Adenomyosis is a common gynaecological disorder that is associated with infertility and miscarriage. We report a case of adenomyosis presented with urinary retention and infertility. The patient successfully conceived spontaneously following GnRHa followed by progestogen therapy. This treatment option might provide a synergistic effect in improving fertility and pregnancy outcome for women with adenomyosis. This modality has no potential surgical risk; it minimises the long-term side effects of GnRHa and also provides luteal support.",
keywords = "adenomyosis, dydrogesterone, gonadotropin releasing hormone agonist, infertility, progestogen",
author = "Dasrilsyah, {Rima Anggrena} and Lim, {Pei Shan} and Ng, {Beng Kwang} and Shafiee, {Mohamad Nasir} and Omar, {Mohd Hashim}",
year = "2016",
month = "8",
day = "1",
doi = "10.1515/hmbci-2015-0061",
language = "English",
volume = "27",
pages = "77--79",
journal = "Hormone Molecular Biology and Clinical Investigation",
issn = "1868-1883",
publisher = "Walter de Gruyter GmbH",
number = "2",

}

TY - JOUR

T1 - Spontaneous conception following GnRHa and progestogen therapy in adenomyosis

AU - Dasrilsyah, Rima Anggrena

AU - Lim, Pei Shan

AU - Ng, Beng Kwang

AU - Shafiee, Mohamad Nasir

AU - Omar, Mohd Hashim

PY - 2016/8/1

Y1 - 2016/8/1

N2 - Adenomyosis is a common gynaecological disorder that is associated with infertility and miscarriage. We report a case of adenomyosis presented with urinary retention and infertility. The patient successfully conceived spontaneously following GnRHa followed by progestogen therapy. This treatment option might provide a synergistic effect in improving fertility and pregnancy outcome for women with adenomyosis. This modality has no potential surgical risk; it minimises the long-term side effects of GnRHa and also provides luteal support.

AB - Adenomyosis is a common gynaecological disorder that is associated with infertility and miscarriage. We report a case of adenomyosis presented with urinary retention and infertility. The patient successfully conceived spontaneously following GnRHa followed by progestogen therapy. This treatment option might provide a synergistic effect in improving fertility and pregnancy outcome for women with adenomyosis. This modality has no potential surgical risk; it minimises the long-term side effects of GnRHa and also provides luteal support.

KW - adenomyosis

KW - dydrogesterone

KW - gonadotropin releasing hormone agonist

KW - infertility

KW - progestogen

UR - http://www.scopus.com/inward/record.url?scp=84989183259&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84989183259&partnerID=8YFLogxK

U2 - 10.1515/hmbci-2015-0061

DO - 10.1515/hmbci-2015-0061

M3 - Review article

VL - 27

SP - 77

EP - 79

JO - Hormone Molecular Biology and Clinical Investigation

JF - Hormone Molecular Biology and Clinical Investigation

SN - 1868-1883

IS - 2

ER -