Splenic tuberculosis presenting as pyrexia of unknown origin

Razlan Hamizah, A. G. Rohana, S. A. Anwar, T. Z. Ong, Hamzaini Abdul Hamid, A. N. Zulkarnaen

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

We report a case of a previously healthy 38-year old lady who presented with prolonged fever and hepatosplenomegaly. Intensive investigations were performed for pyrexia of unknown origin which revealed negative. CT scan of the abdomen showed multiple hypodense lesions which did not respond to broad-spectrum antibiotics. Percutaneous biopsy of the splenic lesion revealed granuloma formation and Langhan's giant cells suggestive of TB. She responded well with anti- TB medication but required extended treatment duration of 24 months due to persistence of the splenic lesion on repeated CT scans. This case illustrates a very rare clinical entity of isolated splenic TB with a therapeutic dilemma following incomplete resolution, despite prolonged treatment.

Original languageEnglish
Pages (from-to)70-71
Number of pages2
JournalMedical Journal of Malaysia
Volume62
Issue number1
Publication statusPublished - Mar 2007

Fingerprint

Splenic Tuberculosis
Langhans Giant Cells
Fever
Granuloma
Abdomen
Anti-Bacterial Agents
Biopsy
Therapeutics

Keywords

  • Pyrexia of unknown origin
  • Spleen
  • Tuberculosis

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Hamizah, R., Rohana, A. G., Anwar, S. A., Ong, T. Z., Abdul Hamid, H., & Zulkarnaen, A. N. (2007). Splenic tuberculosis presenting as pyrexia of unknown origin. Medical Journal of Malaysia, 62(1), 70-71.

Splenic tuberculosis presenting as pyrexia of unknown origin. / Hamizah, Razlan; Rohana, A. G.; Anwar, S. A.; Ong, T. Z.; Abdul Hamid, Hamzaini; Zulkarnaen, A. N.

In: Medical Journal of Malaysia, Vol. 62, No. 1, 03.2007, p. 70-71.

Research output: Contribution to journalArticle

Hamizah, R, Rohana, AG, Anwar, SA, Ong, TZ, Abdul Hamid, H & Zulkarnaen, AN 2007, 'Splenic tuberculosis presenting as pyrexia of unknown origin', Medical Journal of Malaysia, vol. 62, no. 1, pp. 70-71.
Hamizah R, Rohana AG, Anwar SA, Ong TZ, Abdul Hamid H, Zulkarnaen AN. Splenic tuberculosis presenting as pyrexia of unknown origin. Medical Journal of Malaysia. 2007 Mar;62(1):70-71.
Hamizah, Razlan ; Rohana, A. G. ; Anwar, S. A. ; Ong, T. Z. ; Abdul Hamid, Hamzaini ; Zulkarnaen, A. N. / Splenic tuberculosis presenting as pyrexia of unknown origin. In: Medical Journal of Malaysia. 2007 ; Vol. 62, No. 1. pp. 70-71.
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