Solitary fibrous tumour of the submandibular region

A rare entity

Noor Liza Ishak, Primuharsa Putra Sabir Athar Husin, Suria Hayati Md Pauzi, Isa Mohd Rose, Mohd. Razif Mohamad Yunus

Research output: Contribution to journalArticle

Abstract

Solitary fibrous tumours of the head and neck region are extremely rare. The clinical diagnosis is often difficult to establish, and this lesion may be indistinguishable from other soft tissue neoplasms. An 18-year old Chinese gentleman presented with a painless right submandibular swelling which was increasing in size for eight months. A computed tomography scan showed a well-defined solid mass measuring about 2.0 x 2.96 cm in the submandibular region. The tumour was resected and was confined within its capsule. Immunohistochemical staining was strongly positive for CD34, CD 99, and vimentin and negative for desmin, smooth muscle actin (SMA), cytokeratin, S100 and CD68. The microscopic and immunohistochemical profile were compatible with solitary fibrous tumour. Distinguishing solitary fibrous tumours from various spindle neoplasms can be difficult. In view of the resemblance, immunohistochemical staining can help differentiate solitary fibrous tumour from spindle neoplasm.

Original languageEnglish
Pages (from-to)61-63
Number of pages3
JournalMalaysian Journal of Medicine and Health Sciences
Volume12
Issue number2
Publication statusPublished - 1 Jun 2016

Fingerprint

Solitary Fibrous Tumors
Soft Tissue Neoplasms
Staining and Labeling
Neoplasms
Desmin
Vimentin
Keratins
Capsules
Smooth Muscle
Actins
Neck
Head
Tomography

Keywords

  • Solitary fibrous tumour
  • Submandibular

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Solitary fibrous tumour of the submandibular region : A rare entity. / Ishak, Noor Liza; Husin, Primuharsa Putra Sabir Athar; Md Pauzi, Suria Hayati; Rose, Isa Mohd; Mohamad Yunus, Mohd. Razif.

In: Malaysian Journal of Medicine and Health Sciences, Vol. 12, No. 2, 01.06.2016, p. 61-63.

Research output: Contribution to journalArticle

Ishak, Noor Liza ; Husin, Primuharsa Putra Sabir Athar ; Md Pauzi, Suria Hayati ; Rose, Isa Mohd ; Mohamad Yunus, Mohd. Razif. / Solitary fibrous tumour of the submandibular region : A rare entity. In: Malaysian Journal of Medicine and Health Sciences. 2016 ; Vol. 12, No. 2. pp. 61-63.
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