Small cell variant of anaplastic large cell lymphoma with positive immunoreactivity for CD99

Mohd Sidik Shiran, Geok Chin Tan, A. R. Sabariah, P. C. Chye, R. Pathmanathan

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

A 13 year old boy presented with a huge mass on his right arm of 6 months duration. Histopathological examination revealed sheets of malignant small round blue cells with immunopositivity for LCA, CD43, CD45Ro, CD30, EMA, ALK-1 and CD99, and negativity for CD20, TdT, myogenin, myoD1, NSE, bcl-6, bcl-2 and CD10. Fluorescent In-Situ Hybridization (FISH) testing excluded the diagnosis of Ewing's sarcoma/ PNET. Pathologists need to be aware of the diagnosis of a small cell variant of ALCL, as well as of the fact that CD99 expression commonly occurs in cases of ALK-positive ALCL, in order to distinguish this entity from Ewing's sarcoma/PNET.

Original languageEnglish
Pages (from-to)150-151
Number of pages2
JournalMedical Journal of Malaysia
Volume63
Issue number2
Publication statusPublished - Jun 2008

Fingerprint

Primitive Neuroectodermal Tumors
Ewing's Sarcoma
Myogenin
Fluorescence In Situ Hybridization
Anaplastic small cell lymphoma
Pathologists

Keywords

  • Anaplastic large cell lymphoma
  • CD30 positive
  • CD99 positive
  • Small cell variant
  • Soft tissue tumour

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Shiran, M. S., Tan, G. C., Sabariah, A. R., Chye, P. C., & Pathmanathan, R. (2008). Small cell variant of anaplastic large cell lymphoma with positive immunoreactivity for CD99. Medical Journal of Malaysia, 63(2), 150-151.

Small cell variant of anaplastic large cell lymphoma with positive immunoreactivity for CD99. / Shiran, Mohd Sidik; Tan, Geok Chin; Sabariah, A. R.; Chye, P. C.; Pathmanathan, R.

In: Medical Journal of Malaysia, Vol. 63, No. 2, 06.2008, p. 150-151.

Research output: Contribution to journalArticle

Shiran, MS, Tan, GC, Sabariah, AR, Chye, PC & Pathmanathan, R 2008, 'Small cell variant of anaplastic large cell lymphoma with positive immunoreactivity for CD99', Medical Journal of Malaysia, vol. 63, no. 2, pp. 150-151.
Shiran, Mohd Sidik ; Tan, Geok Chin ; Sabariah, A. R. ; Chye, P. C. ; Pathmanathan, R. / Small cell variant of anaplastic large cell lymphoma with positive immunoreactivity for CD99. In: Medical Journal of Malaysia. 2008 ; Vol. 63, No. 2. pp. 150-151.
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