Skeletal-related events among breast and prostate cancer patients

Towards new treatment initiation in malaysia's hospital setting

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

The human skeleton is the most common organ to be affected by metastatic cancer and bone metastases are a major cause of cancer morbidity. The five most frequent cancers in Malaysia among males includes prostate whereas breast cancer is among those in females, both being associated with skeletal lesions. Bone metastases weaken bone structure, causing a range of symptoms and complications thus developing skeletal-related events (SRE). Patients with SRE may require palliative radiotherapy or surgery to bone for pain, having hypercalcaemia, pathologic fractures, and spinal cord compression. These complications contribute to a decline in patient healthrelated quality of life. The multidimensional assessment of health-related quality of life for those patients is important other than considering a beneficial treatment impact on patient survival, since the side effects of treatment and disease symptoms can significantly impact health-related quality of life. Cancer treatment could contribute to significant financial implications for the healthcare system. Therefore, it is essential to assess the health-related quality of life and treatment cost, among prostate and breast cancer patients in countries like Malaysia to rationalized cost-effective way for budget allocation or utilization of health care resources, hence helping in providing more personalized treatment for cancer patients.

Original languageEnglish
Pages (from-to)3357-3362
Number of pages6
JournalAsian Pacific Journal of Cancer Prevention
Volume14
Issue number5
DOIs
Publication statusPublished - 2013

Fingerprint

Malaysia
Prostatic Neoplasms
Breast Neoplasms
Quality of Life
Bone and Bones
Neoplasms
Therapeutics
Neoplasm Metastasis
Bone Neoplasms
Spontaneous Fractures
Spinal Cord Compression
Health Resources
Hypercalcemia
Budgets
Skeleton
Health Care Costs
Prostate
Radiotherapy
Morbidity
Delivery of Health Care

Keywords

  • Bone metastases
  • Breast cancer
  • Cost
  • Prostate cancer
  • Quality of life
  • Skeletal related events

ASJC Scopus subject areas

  • Oncology
  • Cancer Research
  • Public Health, Environmental and Occupational Health
  • Epidemiology
  • Medicine(all)

Cite this

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title = "Skeletal-related events among breast and prostate cancer patients: Towards new treatment initiation in malaysia's hospital setting",
abstract = "The human skeleton is the most common organ to be affected by metastatic cancer and bone metastases are a major cause of cancer morbidity. The five most frequent cancers in Malaysia among males includes prostate whereas breast cancer is among those in females, both being associated with skeletal lesions. Bone metastases weaken bone structure, causing a range of symptoms and complications thus developing skeletal-related events (SRE). Patients with SRE may require palliative radiotherapy or surgery to bone for pain, having hypercalcaemia, pathologic fractures, and spinal cord compression. These complications contribute to a decline in patient healthrelated quality of life. The multidimensional assessment of health-related quality of life for those patients is important other than considering a beneficial treatment impact on patient survival, since the side effects of treatment and disease symptoms can significantly impact health-related quality of life. Cancer treatment could contribute to significant financial implications for the healthcare system. Therefore, it is essential to assess the health-related quality of life and treatment cost, among prostate and breast cancer patients in countries like Malaysia to rationalized cost-effective way for budget allocation or utilization of health care resources, hence helping in providing more personalized treatment for cancer patients.",
keywords = "Bone metastases, Breast cancer, Cost, Prostate cancer, Quality of life, Skeletal related events",
author = "{Wan Puteh}, {Sharifa Ezat} and {Syed Junid}, {Syed Mohamed Al-Junid} and Noraziani Khamis and Zafar Ahmed and Saperi Sulong and Nur, {Amrizal Muhammad} and Aizuddin, {Azimatun Noor} and Fuad Ismail and Norlia Abdullah and {Md. Zainuddin}, Zulkifli and {Mohd Kassim}, {Abdul Yazid} and {Mohamed Haflah}, {Nor Hazla}",
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AU - Syed Junid, Syed Mohamed Al-Junid

AU - Khamis, Noraziani

AU - Ahmed, Zafar

AU - Sulong, Saperi

AU - Nur, Amrizal Muhammad

AU - Aizuddin, Azimatun Noor

AU - Ismail, Fuad

AU - Abdullah, Norlia

AU - Md. Zainuddin, Zulkifli

AU - Mohd Kassim, Abdul Yazid

AU - Mohamed Haflah, Nor Hazla

PY - 2013

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N2 - The human skeleton is the most common organ to be affected by metastatic cancer and bone metastases are a major cause of cancer morbidity. The five most frequent cancers in Malaysia among males includes prostate whereas breast cancer is among those in females, both being associated with skeletal lesions. Bone metastases weaken bone structure, causing a range of symptoms and complications thus developing skeletal-related events (SRE). Patients with SRE may require palliative radiotherapy or surgery to bone for pain, having hypercalcaemia, pathologic fractures, and spinal cord compression. These complications contribute to a decline in patient healthrelated quality of life. The multidimensional assessment of health-related quality of life for those patients is important other than considering a beneficial treatment impact on patient survival, since the side effects of treatment and disease symptoms can significantly impact health-related quality of life. Cancer treatment could contribute to significant financial implications for the healthcare system. Therefore, it is essential to assess the health-related quality of life and treatment cost, among prostate and breast cancer patients in countries like Malaysia to rationalized cost-effective way for budget allocation or utilization of health care resources, hence helping in providing more personalized treatment for cancer patients.

AB - The human skeleton is the most common organ to be affected by metastatic cancer and bone metastases are a major cause of cancer morbidity. The five most frequent cancers in Malaysia among males includes prostate whereas breast cancer is among those in females, both being associated with skeletal lesions. Bone metastases weaken bone structure, causing a range of symptoms and complications thus developing skeletal-related events (SRE). Patients with SRE may require palliative radiotherapy or surgery to bone for pain, having hypercalcaemia, pathologic fractures, and spinal cord compression. These complications contribute to a decline in patient healthrelated quality of life. The multidimensional assessment of health-related quality of life for those patients is important other than considering a beneficial treatment impact on patient survival, since the side effects of treatment and disease symptoms can significantly impact health-related quality of life. Cancer treatment could contribute to significant financial implications for the healthcare system. Therefore, it is essential to assess the health-related quality of life and treatment cost, among prostate and breast cancer patients in countries like Malaysia to rationalized cost-effective way for budget allocation or utilization of health care resources, hence helping in providing more personalized treatment for cancer patients.

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