Sinonasal hybrid tumour involving the anterior skull base

A. Mazita, Balwant Singh Gendeh, A. I. Zainal

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Objective: We report a rare case of sinonasal hybrid tumour within an inverted papilloma. Method: The patient's case history and course of management are presented. The relevant medical literature are reviewed and discussed. Results: A 60-year-old man presented with unilateral nasal obstruction associated with anosmia. An ENT examination revealed a unilateral, left nasal mass. A provisional diagnosis of inverted papilloma was made. The patient underwent a transnasal endoscopic excision of the tumour, which was unfortunately complicated by a cerebrospinal fluid leak. Further treatment of this patient is described. We highlight the features of associated malignancy in inverted papilloma, and the importance of thorough histopathological examination of tissue specimens. Conclusion: Treatment of inverted papilloma with limited involvement of the skull base can be successfully achieved by endoscopic excision. A high index of clinical suspicion, together with meticulous histopathological examination, will enable diagnosis of associated malignancy. This will ensure that appropriate adjuvant treatment is given, resulting in a good clinical outcome.

Original languageEnglish
Pages (from-to)861-863
Number of pages3
JournalJournal of Laryngology and Otology
Volume122
Issue number8
DOIs
Publication statusPublished - Aug 2008

Fingerprint

Inverted Papilloma
Skull Base
Neoplasms
Olfaction Disorders
Nasal Obstruction
Nose
Therapeutics

Keywords

  • Endoscopes
  • Hybrid Tumour
  • Inverted Papilloma
  • Paranasal Sinus Neoplasms

ASJC Scopus subject areas

  • Otorhinolaryngology

Cite this

Sinonasal hybrid tumour involving the anterior skull base. / Mazita, A.; Gendeh, Balwant Singh; Zainal, A. I.

In: Journal of Laryngology and Otology, Vol. 122, No. 8, 08.2008, p. 861-863.

Research output: Contribution to journalArticle

@article{8c42065b358c4010996f89eccb3babc4,
title = "Sinonasal hybrid tumour involving the anterior skull base",
abstract = "Objective: We report a rare case of sinonasal hybrid tumour within an inverted papilloma. Method: The patient's case history and course of management are presented. The relevant medical literature are reviewed and discussed. Results: A 60-year-old man presented with unilateral nasal obstruction associated with anosmia. An ENT examination revealed a unilateral, left nasal mass. A provisional diagnosis of inverted papilloma was made. The patient underwent a transnasal endoscopic excision of the tumour, which was unfortunately complicated by a cerebrospinal fluid leak. Further treatment of this patient is described. We highlight the features of associated malignancy in inverted papilloma, and the importance of thorough histopathological examination of tissue specimens. Conclusion: Treatment of inverted papilloma with limited involvement of the skull base can be successfully achieved by endoscopic excision. A high index of clinical suspicion, together with meticulous histopathological examination, will enable diagnosis of associated malignancy. This will ensure that appropriate adjuvant treatment is given, resulting in a good clinical outcome.",
keywords = "Endoscopes, Hybrid Tumour, Inverted Papilloma, Paranasal Sinus Neoplasms",
author = "A. Mazita and Gendeh, {Balwant Singh} and Zainal, {A. I.}",
year = "2008",
month = "8",
doi = "10.1017/S0022215107000060",
language = "English",
volume = "122",
pages = "861--863",
journal = "Journal of Laryngology and Otology",
issn = "0022-2151",
publisher = "Cambridge University Press",
number = "8",

}

TY - JOUR

T1 - Sinonasal hybrid tumour involving the anterior skull base

AU - Mazita, A.

AU - Gendeh, Balwant Singh

AU - Zainal, A. I.

PY - 2008/8

Y1 - 2008/8

N2 - Objective: We report a rare case of sinonasal hybrid tumour within an inverted papilloma. Method: The patient's case history and course of management are presented. The relevant medical literature are reviewed and discussed. Results: A 60-year-old man presented with unilateral nasal obstruction associated with anosmia. An ENT examination revealed a unilateral, left nasal mass. A provisional diagnosis of inverted papilloma was made. The patient underwent a transnasal endoscopic excision of the tumour, which was unfortunately complicated by a cerebrospinal fluid leak. Further treatment of this patient is described. We highlight the features of associated malignancy in inverted papilloma, and the importance of thorough histopathological examination of tissue specimens. Conclusion: Treatment of inverted papilloma with limited involvement of the skull base can be successfully achieved by endoscopic excision. A high index of clinical suspicion, together with meticulous histopathological examination, will enable diagnosis of associated malignancy. This will ensure that appropriate adjuvant treatment is given, resulting in a good clinical outcome.

AB - Objective: We report a rare case of sinonasal hybrid tumour within an inverted papilloma. Method: The patient's case history and course of management are presented. The relevant medical literature are reviewed and discussed. Results: A 60-year-old man presented with unilateral nasal obstruction associated with anosmia. An ENT examination revealed a unilateral, left nasal mass. A provisional diagnosis of inverted papilloma was made. The patient underwent a transnasal endoscopic excision of the tumour, which was unfortunately complicated by a cerebrospinal fluid leak. Further treatment of this patient is described. We highlight the features of associated malignancy in inverted papilloma, and the importance of thorough histopathological examination of tissue specimens. Conclusion: Treatment of inverted papilloma with limited involvement of the skull base can be successfully achieved by endoscopic excision. A high index of clinical suspicion, together with meticulous histopathological examination, will enable diagnosis of associated malignancy. This will ensure that appropriate adjuvant treatment is given, resulting in a good clinical outcome.

KW - Endoscopes

KW - Hybrid Tumour

KW - Inverted Papilloma

KW - Paranasal Sinus Neoplasms

UR - http://www.scopus.com/inward/record.url?scp=47549105531&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=47549105531&partnerID=8YFLogxK

U2 - 10.1017/S0022215107000060

DO - 10.1017/S0022215107000060

M3 - Article

VL - 122

SP - 861

EP - 863

JO - Journal of Laryngology and Otology

JF - Journal of Laryngology and Otology

SN - 0022-2151

IS - 8

ER -