Serum iron status in Orang Asli children living in endemic areas of soil-transmitted helminths

U. Nor Aini, M. S. Hesham Al-Mekhlafi, `Azlin Muhammad @ Mohd Yasin, A. Shaik, A. Sa'iah, M. S. Fatmah, M. G. Ismail, M. S. Ahmad Firdaus, M. Y. Aisah, A. R. Rozlida, Norhayati Moktar

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Abstract

We conducted a cross sectional study to examine the association of intestinal parasitic infections and protein energy malnutrition (PEM) with iron-status indicators and anaemia among Orang Asli children in Selangor, Malaysia. A total of 281 children aged 2 - 15 years were studied. The data were collected using structured questionnaires, anthropometric measurements and laboratory analysis for blood and faecal samples. All children were infected either by A. lumbricoides, T. trichiura or hookworm and almost 19%, 26% and 3% of the children had severe infection of ascariasis, trichuriasis and hookworm infection respectively. The prevalence of giardiasis among them was 24.9%. Overall, 41.5% of the children were anaemic (haemoglobin < 11.0 g/dL). Of these 61.0% of the children had iron deficiency and 36.5% had iron deficiency anaemia (IDA), which accounted for 88.0% of anaemia in this population. Severe trichuriasis had the most significant correlation with anaemia and iron deficiency in this population. It contributed to low concentrations of haemoglobin, serum iron and serum ferritin and high total iron binding capacity (TIBC). Significant underweight and stunting were associated with low concentrations of haemoglobin and serum iron while significant wasting was significantly associated with low concentration of serum ferritin. Logistic regression analysis confirmed that severe trichuriasis was a strong predictor of IDA. It also confirmed that children who were significantly underweight and whose mother was working were independent predictors of IDA in this population.

Original languageEnglish
Pages (from-to)724-730
Number of pages7
JournalAsia Pacific Journal of Clinical Nutrition
Volume16
Issue number4
Publication statusPublished - Dec 2007

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Helminths
Soil
Iron
Trichuriasis
Iron-Deficiency Anemias
Serum
Hemoglobins
Thinness
Ferritins
Anemia
Hookworm Infections
Growth Disorders
Ascariasis
Population
Giardiasis
Ancylostomatoidea
Protein-Energy Malnutrition
Parasitic Diseases
Malaysia
Cross-Sectional Studies

Keywords

  • Iron deficiency anaemia
  • Malaysia
  • Orang Asli children
  • Protein-energy malnutrition
  • Soil-transmitted helminthiases

ASJC Scopus subject areas

  • Medicine (miscellaneous)

Cite this

Nor Aini, U., Hesham Al-Mekhlafi, M. S., Muhammad @ Mohd Yasin, A., Shaik, A., Sa'iah, A., Fatmah, M. S., ... Moktar, N. (2007). Serum iron status in Orang Asli children living in endemic areas of soil-transmitted helminths. Asia Pacific Journal of Clinical Nutrition, 16(4), 724-730.

Serum iron status in Orang Asli children living in endemic areas of soil-transmitted helminths. / Nor Aini, U.; Hesham Al-Mekhlafi, M. S.; Muhammad @ Mohd Yasin, `Azlin; Shaik, A.; Sa'iah, A.; Fatmah, M. S.; Ismail, M. G.; Ahmad Firdaus, M. S.; Aisah, M. Y.; Rozlida, A. R.; Moktar, Norhayati.

In: Asia Pacific Journal of Clinical Nutrition, Vol. 16, No. 4, 12.2007, p. 724-730.

Research output: Contribution to journalArticle

Nor Aini, U, Hesham Al-Mekhlafi, MS, Muhammad @ Mohd Yasin, A, Shaik, A, Sa'iah, A, Fatmah, MS, Ismail, MG, Ahmad Firdaus, MS, Aisah, MY, Rozlida, AR & Moktar, N 2007, 'Serum iron status in Orang Asli children living in endemic areas of soil-transmitted helminths', Asia Pacific Journal of Clinical Nutrition, vol. 16, no. 4, pp. 724-730.
Nor Aini, U. ; Hesham Al-Mekhlafi, M. S. ; Muhammad @ Mohd Yasin, `Azlin ; Shaik, A. ; Sa'iah, A. ; Fatmah, M. S. ; Ismail, M. G. ; Ahmad Firdaus, M. S. ; Aisah, M. Y. ; Rozlida, A. R. ; Moktar, Norhayati. / Serum iron status in Orang Asli children living in endemic areas of soil-transmitted helminths. In: Asia Pacific Journal of Clinical Nutrition. 2007 ; Vol. 16, No. 4. pp. 724-730.
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abstract = "We conducted a cross sectional study to examine the association of intestinal parasitic infections and protein energy malnutrition (PEM) with iron-status indicators and anaemia among Orang Asli children in Selangor, Malaysia. A total of 281 children aged 2 - 15 years were studied. The data were collected using structured questionnaires, anthropometric measurements and laboratory analysis for blood and faecal samples. All children were infected either by A. lumbricoides, T. trichiura or hookworm and almost 19{\%}, 26{\%} and 3{\%} of the children had severe infection of ascariasis, trichuriasis and hookworm infection respectively. The prevalence of giardiasis among them was 24.9{\%}. Overall, 41.5{\%} of the children were anaemic (haemoglobin < 11.0 g/dL). Of these 61.0{\%} of the children had iron deficiency and 36.5{\%} had iron deficiency anaemia (IDA), which accounted for 88.0{\%} of anaemia in this population. Severe trichuriasis had the most significant correlation with anaemia and iron deficiency in this population. It contributed to low concentrations of haemoglobin, serum iron and serum ferritin and high total iron binding capacity (TIBC). Significant underweight and stunting were associated with low concentrations of haemoglobin and serum iron while significant wasting was significantly associated with low concentration of serum ferritin. Logistic regression analysis confirmed that severe trichuriasis was a strong predictor of IDA. It also confirmed that children who were significantly underweight and whose mother was working were independent predictors of IDA in this population.",
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AU - Shaik, A.

AU - Sa'iah, A.

AU - Fatmah, M. S.

AU - Ismail, M. G.

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