Serum ferritin and lactate dehydrogenase in a case of hemophagocytic lymphohistiocytosis.

Leong Chooi Fun, S. K. Cheong, Noor Hamidah Hussin, O. Ainoon, Y. Kannaheswary

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Abstract

A 40-day-old baby girl presented with intermittent fever, lymphadenopathy, massive hepatosplenomegaly, progressive pancytopenia and features of disseminated intravascular coagulopathy. A bone marrow aspiration was performed and showed florid histiocytic proliferation with marked hemophagocytosis. Based on the diagnostic guideline for Hemophagocytic Lymphohistiocytosis proposed by the Familial Hemophagocytic Lymphohistiocytosis Study Group of Histiocyte Society, this patient has fulfilled most of the criteria. We have also found that serum ferritin and lactate dehydrogenase to be very high in this patient. It remains uncertain whether the disorder is reactive or neoplastic.

Original languageEnglish
Pages (from-to)103-108
Number of pages6
JournalThe Malaysian journal of pathology
Volume20
Issue number2
Publication statusPublished - 1998

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Hemophagocytic Lymphohistiocytosis
Ferritins
L-Lactate Dehydrogenase
Adjustment Disorders
Pancytopenia
Histiocytes
Serum
Fever
Bone Marrow
Guidelines
Lymphadenopathy
Aspirations (Psychology)

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Serum ferritin and lactate dehydrogenase in a case of hemophagocytic lymphohistiocytosis. / Chooi Fun, Leong; Cheong, S. K.; Hussin, Noor Hamidah; Ainoon, O.; Kannaheswary, Y.

In: The Malaysian journal of pathology, Vol. 20, No. 2, 1998, p. 103-108.

Research output: Contribution to journalArticle

Chooi Fun, L, Cheong, SK, Hussin, NH, Ainoon, O & Kannaheswary, Y 1998, 'Serum ferritin and lactate dehydrogenase in a case of hemophagocytic lymphohistiocytosis.', The Malaysian journal of pathology, vol. 20, no. 2, pp. 103-108.
Chooi Fun, Leong ; Cheong, S. K. ; Hussin, Noor Hamidah ; Ainoon, O. ; Kannaheswary, Y. / Serum ferritin and lactate dehydrogenase in a case of hemophagocytic lymphohistiocytosis. In: The Malaysian journal of pathology. 1998 ; Vol. 20, No. 2. pp. 103-108.
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