Seroprevalence of acute dengue in a Malaysian tertiary medical centre

Chuan Hun Ding, Noor Zetti Zainol Rashid, Md. Mostafizur Rahman, Nan Feng Khang, Wan Ngor Low, Nurabrar Hussin, Melissa Iqlima Marzuki, Alyaa Nadhira Jaafar, Nurul Ain’ Nabilla Roslan, Terukumar Chandrasekaran

Research output: Contribution to journalArticle

Abstract

Objectives: The aims of this study were to determine the seroprevalence of acute dengue in Universiti Kebangsaan Malaysia (UKM) Medical Centre and its correlation with selected haematological and biochemical parameters. Methods: This cross-sectional study was conducted from January to June 2015. A patient was serologically diagnosed with acute dengue if the dengue virus IgG, IgM or NS-1 antigen was reactive. Results: Out of 1,774 patients suspected to have acute dengue, 1,153 were serologically diagnosed with the infection, resulting in a seroprevalence of 64.9%. Dengue-positive patients had a lower mean platelet count (89 x 109/L) compared to the dengue-negative patients (171 x 109/L) (p9/L vs. 7.2 x 109/L; p

Original languageEnglish
Pages (from-to)495-498
Number of pages4
JournalPakistan Journal of Medical Sciences
Volume32
Issue number2
DOIs
Publication statusPublished - 2016

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Dengue
Seroepidemiologic Studies
Dengue Virus
Malaysia
Platelet Count
Immunoglobulin M
Cross-Sectional Studies
Immunoglobulin G
Antigens
Infection

Keywords

  • Dengue
  • DENV
  • IgG
  • IgM
  • NS1
  • Seroprevalence

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Seroprevalence of acute dengue in a Malaysian tertiary medical centre. / Ding, Chuan Hun; Zainol Rashid, Noor Zetti; Rahman, Md. Mostafizur; Khang, Nan Feng; Low, Wan Ngor; Hussin, Nurabrar; Marzuki, Melissa Iqlima; Jaafar, Alyaa Nadhira; Roslan, Nurul Ain’ Nabilla; Chandrasekaran, Terukumar.

In: Pakistan Journal of Medical Sciences, Vol. 32, No. 2, 2016, p. 495-498.

Research output: Contribution to journalArticle

Ding, CH, Zainol Rashid, NZ, Rahman, MM, Khang, NF, Low, WN, Hussin, N, Marzuki, MI, Jaafar, AN, Roslan, NAN & Chandrasekaran, T 2016, 'Seroprevalence of acute dengue in a Malaysian tertiary medical centre', Pakistan Journal of Medical Sciences, vol. 32, no. 2, pp. 495-498. https://doi.org/10.12669/pjms.322.9320
Ding, Chuan Hun ; Zainol Rashid, Noor Zetti ; Rahman, Md. Mostafizur ; Khang, Nan Feng ; Low, Wan Ngor ; Hussin, Nurabrar ; Marzuki, Melissa Iqlima ; Jaafar, Alyaa Nadhira ; Roslan, Nurul Ain’ Nabilla ; Chandrasekaran, Terukumar. / Seroprevalence of acute dengue in a Malaysian tertiary medical centre. In: Pakistan Journal of Medical Sciences. 2016 ; Vol. 32, No. 2. pp. 495-498.
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