Screening for antibacterial agents in three species of sea cucumbers from coastal areas of Sabah

B. H. Ridzwan, M. A. Kaswandi, Y. Azman, M. Fuad

    Research output: Contribution to journalArticle

    52 Citations (Scopus)

    Abstract

    1. 1. Three species of sea cucumbers found in the Sabah coastal areas were screened for the presence of antibacterial activity using three methods of extraction. Tests were conducted in vitro using the agar absorption method. 2. 2. Both the lipid extract and the methanol-solvent extract from Holothuria atra, Holothuria scabra and Bohadshia argus were found to show no antibacterial activity. 3. 3. Phosphate-buffered saline (PBS) from H. atra and B. argus, however, inhibited the growth of all gram-positive and gram-negative bacteria. 4. 4. Comparisons were also made between extracts from the outer layer of H. atra and its inner part, and it was found that the extract from the outer layer showed less bacterial growth inhibition property. 5. 5. The bacterial growth inhibition property of the PBS extract from H. atra, however, is dependent on the extract's concentration. Bacterial growth inhibition was apparent after 48 hr incubation.

    Original languageEnglish
    Pages (from-to)1539-1543
    Number of pages5
    JournalGeneral Pharmacology
    Volume26
    Issue number7
    DOIs
    Publication statusPublished - 1995

    Fingerprint

    Sea Cucumbers
    Malaysia
    Holothuria
    Anti-Bacterial Agents
    Growth
    Phosphates
    Gram-Negative Bacteria
    Agar
    Methanol
    Lipids

    ASJC Scopus subject areas

    • Pharmacology

    Cite this

    Screening for antibacterial agents in three species of sea cucumbers from coastal areas of Sabah. / Ridzwan, B. H.; Kaswandi, M. A.; Azman, Y.; Fuad, M.

    In: General Pharmacology, Vol. 26, No. 7, 1995, p. 1539-1543.

    Research output: Contribution to journalArticle

    Ridzwan, B. H. ; Kaswandi, M. A. ; Azman, Y. ; Fuad, M. / Screening for antibacterial agents in three species of sea cucumbers from coastal areas of Sabah. In: General Pharmacology. 1995 ; Vol. 26, No. 7. pp. 1539-1543.
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