Scedosporium apiospermum fungaemia: The ramification of broad-spectrum antimicrobial treatments

Chuan Hun Ding, Muttaqillah Najihan Abdul Samat, Md. Mostafizur Rahman, N. Z Z Abidin, S. Biswas, Tzar Mohd Nizam Khaithir

Research output: Contribution to journalArticle

Abstract

Scedosporium apiospermum is a cosmopolitan mycotic agent with unique characteristics. This is a case of a 65-year-old immunocompetent patient who presented with shortness of breath and fever. Consolidation was observed in both lung fields on chest X-ray. A diagnosis of aspiration pneumonia was made. Extended spectrum β-lactamase (ESBL)-producing Klebsiella pneumoniae was identified from his tracheal aspirate and imipenem was administered. Initial blood cultures were negative but after 10 days on imipenem, Candida glabrata was isolated. Amphotericin B was added to the treatment regimen, but after a week on this antifungal, Scedosporium apiospermum was identified from the blood. The patient succumbed to illness before a change in the antifungal regimen. The case highlights the unwelcome consequence of using a broad spectrum antibiotic and later a broad spectrum antifungal agent.

Original languageEnglish
Pages (from-to)326-328
Number of pages3
JournalBangladesh Journal of Medical Science
Volume13
Issue number3
DOIs
Publication statusPublished - 2014

Fingerprint

Scedosporium
Fungemia
Imipenem
Candida glabrata
Aspiration Pneumonia
Antifungal Agents
Klebsiella pneumoniae
Amphotericin B
Dyspnea
Fever
Thorax
X-Rays
Anti-Bacterial Agents
Lung
Therapeutics

Keywords

  • Amphotericin B
  • broad spectrum
  • Fungaemia
  • Pseudallescheria boydii
  • Scedosporium apiospermum

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Scedosporium apiospermum fungaemia : The ramification of broad-spectrum antimicrobial treatments. / Ding, Chuan Hun; Abdul Samat, Muttaqillah Najihan; Rahman, Md. Mostafizur; Abidin, N. Z Z; Biswas, S.; Khaithir, Tzar Mohd Nizam.

In: Bangladesh Journal of Medical Science, Vol. 13, No. 3, 2014, p. 326-328.

Research output: Contribution to journalArticle

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