Risk factors for stroke and predictors of one-month mortality

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Abstract

Background: Stroke is the third most common cause of death in Malaysia. The prevalence of risk factors and predictors of mortality of stroke in Malaysia are poorly understood. Aim: To identify the prevalence of major risk factors for stroke and to determine predictors of one-month mortality. Method: Prospective study of all stroke patients admitted to Penang Hospital between December 1998 and November 1999. All patients were subjected to brain CT. Predictors of one-month mortality: systolic and diastolic hypertension, hyperglycaemia, type of stroke, age >70, poor Glasgow coma score (GCS) on admission and deterioration of score were assessed. Results: A total of 246 (139 male and 107 female) patients were included. Median age was 65 years. Hypertension was the commonest risk factor (71.5%) followed by diabetes mellitus (40.2%) and hyperlipidaemia (37%). 74.8% of the cases were ischaemic in origin and 25.2% haemorrhagic. Mortality at one month was 20.3%. Using multivariate analysis and logistic regression, deterioration of GCS (OR=46.04), poor GCS on admission (OR= 12.35) and haemorrhagic stroke (OR=3.45) were independent predictors of one-month mortality. Conclusion: Hypertension and diabetes mellitus are the commonest risk factors of stroke among patients admitted to a tertiary hospital in Malaysia. Significant predictors of one-month mortality include the admission GCS, deterioration of GCS and haemorrhagic stroke.

Original languageEnglish
Pages (from-to)517-521
Number of pages5
JournalSingapore Medical Journal
Volume43
Issue number10
Publication statusPublished - 1 Oct 2002

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Stroke
Coma
Mortality
Malaysia
Hypertension
Diabetes Mellitus
Hyperlipidemias
Tertiary Care Centers
Hyperglycemia
Cause of Death
Multivariate Analysis
Logistic Models
Prospective Studies
Brain

Keywords

  • Glasgow coma scale
  • Haemorrhagic stroke
  • Ischaemic stroke

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Risk factors for stroke and predictors of one-month mortality. / Ong, T. Z.; Ali, Raymond Azman.

In: Singapore Medical Journal, Vol. 43, No. 10, 01.10.2002, p. 517-521.

Research output: Contribution to journalArticle

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AB - Background: Stroke is the third most common cause of death in Malaysia. The prevalence of risk factors and predictors of mortality of stroke in Malaysia are poorly understood. Aim: To identify the prevalence of major risk factors for stroke and to determine predictors of one-month mortality. Method: Prospective study of all stroke patients admitted to Penang Hospital between December 1998 and November 1999. All patients were subjected to brain CT. Predictors of one-month mortality: systolic and diastolic hypertension, hyperglycaemia, type of stroke, age >70, poor Glasgow coma score (GCS) on admission and deterioration of score were assessed. Results: A total of 246 (139 male and 107 female) patients were included. Median age was 65 years. Hypertension was the commonest risk factor (71.5%) followed by diabetes mellitus (40.2%) and hyperlipidaemia (37%). 74.8% of the cases were ischaemic in origin and 25.2% haemorrhagic. Mortality at one month was 20.3%. Using multivariate analysis and logistic regression, deterioration of GCS (OR=46.04), poor GCS on admission (OR= 12.35) and haemorrhagic stroke (OR=3.45) were independent predictors of one-month mortality. Conclusion: Hypertension and diabetes mellitus are the commonest risk factors of stroke among patients admitted to a tertiary hospital in Malaysia. Significant predictors of one-month mortality include the admission GCS, deterioration of GCS and haemorrhagic stroke.

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