Risk factors and prediction of leptospiral seropositivity among dogs and dog handlers in Malaysia

Soon Heng Goh, Rosnah Ismail, Seng Fong Lau, Puteri Azaziah Megat Abdul Rani, Taznim Begam Mohd Mohidin, Faiz Daud, Abdul Rani Bahaman, Siti Khairani-Bejo, Rozanaliza Radzi, Kuan Hua Khor

Research output: Contribution to journalArticle

Abstract

This study determined the potential risk factors that may contribute to seropositivity among dogs and dog handlers from working dog and dog shelter institutions. Data was collected from dogs (n = 266) and dog handlers (n = 161) using a standardised guided questionnaire. Serum obtained from the dogs and dog handlers was tested using the microscopic agglutination test (MAT). A logistic regression analysis was used to predict leptospiral seropositivity of dogs and dog handlers based on potential risk factors. A total of 22.2% of dogs and 21.7% of dog handlers were seropositive. The significant predictors for the dogs’ seropositivity were presence of rats (OR = 4.61 (95% CI: 1.05, 20.33), p = 0.043) and shared common area (OR = 5.12 (95% CI: 1.94, 13.46), p = 0.001) within the organisation. Significant predictor for dog handler seropositivity was contact time with the dogs of more than six hours/day (OR = 3.28 (95% CI: 1.28, 8.40), p = 0.013) after controlling for the effect of other risk factors such as small mammal contact, rat infestation at home, flooding at housing area (within three months) and urban locality. The exposure to various disease sources identified poses risk to dogs and dog handlers. Risk could be reduced with adequate application of protection at work while handling dogs and thus limiting contact with these sources and reducing exposure to infection.

Original languageEnglish
Article number1499
JournalInternational journal of environmental research and public health
Volume16
Issue number9
DOIs
Publication statusPublished - 1 May 2019

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Malaysia
Dogs
Agglutination Tests

Keywords

  • Dog handlers
  • Leptospirosis
  • MAT
  • Seroprevalence
  • Shelter dog
  • Working dogs

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health
  • Health, Toxicology and Mutagenesis

Cite this

Risk factors and prediction of leptospiral seropositivity among dogs and dog handlers in Malaysia. / Goh, Soon Heng; Ismail, Rosnah; Lau, Seng Fong; Rani, Puteri Azaziah Megat Abdul; Mohidin, Taznim Begam Mohd; Daud, Faiz; Bahaman, Abdul Rani; Khairani-Bejo, Siti; Radzi, Rozanaliza; Khor, Kuan Hua.

In: International journal of environmental research and public health, Vol. 16, No. 9, 1499, 01.05.2019.

Research output: Contribution to journalArticle

Goh, Soon Heng ; Ismail, Rosnah ; Lau, Seng Fong ; Rani, Puteri Azaziah Megat Abdul ; Mohidin, Taznim Begam Mohd ; Daud, Faiz ; Bahaman, Abdul Rani ; Khairani-Bejo, Siti ; Radzi, Rozanaliza ; Khor, Kuan Hua. / Risk factors and prediction of leptospiral seropositivity among dogs and dog handlers in Malaysia. In: International journal of environmental research and public health. 2019 ; Vol. 16, No. 9.
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abstract = "This study determined the potential risk factors that may contribute to seropositivity among dogs and dog handlers from working dog and dog shelter institutions. Data was collected from dogs (n = 266) and dog handlers (n = 161) using a standardised guided questionnaire. Serum obtained from the dogs and dog handlers was tested using the microscopic agglutination test (MAT). A logistic regression analysis was used to predict leptospiral seropositivity of dogs and dog handlers based on potential risk factors. A total of 22.2{\%} of dogs and 21.7{\%} of dog handlers were seropositive. The significant predictors for the dogs’ seropositivity were presence of rats (OR = 4.61 (95{\%} CI: 1.05, 20.33), p = 0.043) and shared common area (OR = 5.12 (95{\%} CI: 1.94, 13.46), p = 0.001) within the organisation. Significant predictor for dog handler seropositivity was contact time with the dogs of more than six hours/day (OR = 3.28 (95{\%} CI: 1.28, 8.40), p = 0.013) after controlling for the effect of other risk factors such as small mammal contact, rat infestation at home, flooding at housing area (within three months) and urban locality. The exposure to various disease sources identified poses risk to dogs and dog handlers. Risk could be reduced with adequate application of protection at work while handling dogs and thus limiting contact with these sources and reducing exposure to infection.",
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