Resolution of acanthosis nigricans following curative gastric carcinoma resection

A. V. Jagwani, R. Reynu, Affirul Chairil bin Affirul, M. T. Mustafa, Nik Ritza Kosai Nik Mahmood

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

We discuss a 48-year old, who presented with upper epigastrium pain associated with early satiety and significant weight loss. Physical examination revealed a thickening and darkening of skins around the skin folds, scalp, back and front of abdomen. A diagnosis of gastro-esophageal junction adenocarcinoma was confirmed by oesophagogastroduodenoscopy (OGDS) and biopsy. The biopsy of the skin lesion revealed a diagnosis of acanthosis nigricans, He underwent a total gastrectomy followed by adjuvant chemo-radiotherapy. Recovery is unremarkable. Interestingly, the skin lesions disappear following our therapy. We believe this may be attributed to the treatment of the malignancy. We highlight the interesting association, pathophysiology and therapy.

Original languageEnglish
Pages (from-to)99-100
Number of pages2
JournalClinica Terapeutica
Volume167
Issue number4
DOIs
Publication statusPublished - 2016

Fingerprint

Acanthosis Nigricans
Stomach
Carcinoma
Skin
Digestive System Endoscopy
Biopsy
Adjuvant Radiotherapy
Gastrectomy
Scalp
Abdomen
Physical Examination
Weight Loss
Adenocarcinoma
Therapeutics
Pain
Neoplasms

Keywords

  • Acanthosissupraclavicular
  • Adenocarcinoma
  • Dermatology
  • Gastrectomy

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Resolution of acanthosis nigricans following curative gastric carcinoma resection. / Jagwani, A. V.; Reynu, R.; bin Affirul, Affirul Chairil; Mustafa, M. T.; Nik Mahmood, Nik Ritza Kosai.

In: Clinica Terapeutica, Vol. 167, No. 4, 2016, p. 99-100.

Research output: Contribution to journalArticle

Jagwani, A. V. ; Reynu, R. ; bin Affirul, Affirul Chairil ; Mustafa, M. T. ; Nik Mahmood, Nik Ritza Kosai. / Resolution of acanthosis nigricans following curative gastric carcinoma resection. In: Clinica Terapeutica. 2016 ; Vol. 167, No. 4. pp. 99-100.
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