Resistance of Pseudomonas pseudomallei to normal human serum bactericidal action

G. Ismail, N. Razak, R. Mohamed, N. Embi, Mohammed Noor Embi

Research output: Contribution to journalArticle

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Abstract

The effect of human normal serum (HNS) on Pseudomonas pseudomallei was determined. It is apparent from our data that the organism is resistant to the normal serum bactericidal mechanism. Ancillary experiments to confirm this serum-resistant property of P. pseudomallei were done by examining the effects of growth phase conditions of the bacteria (i.e., logarithmic and stationary phases) and different buffered systems used as diluent in our bactericidal assay. Results obtained showed similar degree of resistance to serum bactericidal killing by 5 strains of the organisms tested. The possible survival advantage of serum-resistant property to P. pseudomallei as bacterial pathogens known to invade the blood stream is discussed.

Original languageEnglish
Pages (from-to)645-652
Number of pages8
JournalMicrobiology and Immunology
Volume32
Issue number7
Publication statusPublished - 1988

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Burkholderia pseudomallei
Serum
Bacteria
Survival
Growth

ASJC Scopus subject areas

  • Immunology and Microbiology(all)
  • Microbiology
  • Microbiology (medical)

Cite this

Resistance of Pseudomonas pseudomallei to normal human serum bactericidal action. / Ismail, G.; Razak, N.; Mohamed, R.; Embi, N.; Embi, Mohammed Noor.

In: Microbiology and Immunology, Vol. 32, No. 7, 1988, p. 645-652.

Research output: Contribution to journalArticle

Ismail, G, Razak, N, Mohamed, R, Embi, N & Embi, MN 1988, 'Resistance of Pseudomonas pseudomallei to normal human serum bactericidal action', Microbiology and Immunology, vol. 32, no. 7, pp. 645-652.
Ismail, G. ; Razak, N. ; Mohamed, R. ; Embi, N. ; Embi, Mohammed Noor. / Resistance of Pseudomonas pseudomallei to normal human serum bactericidal action. In: Microbiology and Immunology. 1988 ; Vol. 32, No. 7. pp. 645-652.
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