Refractive index and sensing of glucose molarities determined using Au-Cr K-SPR at 670/785 nm wavelength

P. Susthitha Menon N V Visvanathan, Budi Mulyanti, Nur Akmar Jamil, Chandra Wulandari, Harbi Setyo Nugroho, Gan Siew Mei, Noor Faizah Zainul Abidin, Lilik Hasanah, Roer Eka Pawinanto, Dilla Duryha Berhanuddin

Research output: Contribution to journalArticle

Abstract

In this paper, we determine the optical refractive indices of different molarities of glucose using nano-laminated gold/chromium (Au-Cr) thin film via Kretschmann-based Surface Plasmon Resonance (K-SPR) sensing with angular interrogation. The nano-laminated Au-Cr K-SPR sensor detects the glucose presence in low- and high-concentration of 4-12 mmol/L and 55-277 mmol/L, respectively, under the exposure of 670 nm and 785 nm optical wavelengths. The experimental results showed that the minimum limit of detection (LOD) of Au-Cr K-SPR is 4 mmol/L and the glucose sensor sensitivities are in average of 3.41 o/M and 2.73o/M at 670 nm and 785 nm optical wavelength, respectively. Stable sensitivity for each concentration also shown from the sensorgram results, indicates the stable performance of nanolaminated Au-Cr SPR sensor to detect glucose in the range from mmol/L up to dmol/L. Values of refractive indices for glucose molarities obtained are 1.33187 (4 mmol/L) and 1.3191 (4 mmol/L) at 670 and 785 nm wavelength, respectively. These RI values are beneficial for numerical simulation of glucose sensors using nano-laminated Au-Cr thin films which have been reported for the first time. The sensor can be eventually deployed in integrated photonic sensing devices comprising of multiple analyte detection for lab-on-chip (LoC) and point-of care (PoC) applications.

Original languageEnglish
Pages (from-to)1259-1265
Number of pages7
JournalSains Malaysiana
Volume48
Issue number6
DOIs
Publication statusPublished - 1 Jan 2019

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surface plasmon resonance
glucose
refractivity
wavelengths
sensors
interrogation
thin films
low concentrations
chromium
chips
photonics
gold
sensitivity
simulation

Keywords

  • Angular interrogation
  • Glucose sensor
  • Gold/chromium
  • Kretschmann
  • Nano-laminated
  • Refractive index
  • Surface plasmon resonance

ASJC Scopus subject areas

  • General

Cite this

Refractive index and sensing of glucose molarities determined using Au-Cr K-SPR at 670/785 nm wavelength. / N V Visvanathan, P. Susthitha Menon; Mulyanti, Budi; Jamil, Nur Akmar; Wulandari, Chandra; Nugroho, Harbi Setyo; Mei, Gan Siew; Zainul Abidin, Noor Faizah; Hasanah, Lilik; Pawinanto, Roer Eka; Berhanuddin, Dilla Duryha.

In: Sains Malaysiana, Vol. 48, No. 6, 01.01.2019, p. 1259-1265.

Research output: Contribution to journalArticle

N V Visvanathan, PSM, Mulyanti, B, Jamil, NA, Wulandari, C, Nugroho, HS, Mei, GS, Zainul Abidin, NF, Hasanah, L, Pawinanto, RE & Berhanuddin, DD 2019, 'Refractive index and sensing of glucose molarities determined using Au-Cr K-SPR at 670/785 nm wavelength', Sains Malaysiana, vol. 48, no. 6, pp. 1259-1265. https://doi.org/10.17576/jsm-2019-4806-13
N V Visvanathan, P. Susthitha Menon ; Mulyanti, Budi ; Jamil, Nur Akmar ; Wulandari, Chandra ; Nugroho, Harbi Setyo ; Mei, Gan Siew ; Zainul Abidin, Noor Faizah ; Hasanah, Lilik ; Pawinanto, Roer Eka ; Berhanuddin, Dilla Duryha. / Refractive index and sensing of glucose molarities determined using Au-Cr K-SPR at 670/785 nm wavelength. In: Sains Malaysiana. 2019 ; Vol. 48, No. 6. pp. 1259-1265.
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abstract = "In this paper, we determine the optical refractive indices of different molarities of glucose using nano-laminated gold/chromium (Au-Cr) thin film via Kretschmann-based Surface Plasmon Resonance (K-SPR) sensing with angular interrogation. The nano-laminated Au-Cr K-SPR sensor detects the glucose presence in low- and high-concentration of 4-12 mmol/L and 55-277 mmol/L, respectively, under the exposure of 670 nm and 785 nm optical wavelengths. The experimental results showed that the minimum limit of detection (LOD) of Au-Cr K-SPR is 4 mmol/L and the glucose sensor sensitivities are in average of 3.41 o/M and 2.73o/M at 670 nm and 785 nm optical wavelength, respectively. Stable sensitivity for each concentration also shown from the sensorgram results, indicates the stable performance of nanolaminated Au-Cr SPR sensor to detect glucose in the range from mmol/L up to dmol/L. Values of refractive indices for glucose molarities obtained are 1.33187 (4 mmol/L) and 1.3191 (4 mmol/L) at 670 and 785 nm wavelength, respectively. These RI values are beneficial for numerical simulation of glucose sensors using nano-laminated Au-Cr thin films which have been reported for the first time. The sensor can be eventually deployed in integrated photonic sensing devices comprising of multiple analyte detection for lab-on-chip (LoC) and point-of care (PoC) applications.",
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AU - N V Visvanathan, P. Susthitha Menon

AU - Mulyanti, Budi

AU - Jamil, Nur Akmar

AU - Wulandari, Chandra

AU - Nugroho, Harbi Setyo

AU - Mei, Gan Siew

AU - Zainul Abidin, Noor Faizah

AU - Hasanah, Lilik

AU - Pawinanto, Roer Eka

AU - Berhanuddin, Dilla Duryha

PY - 2019/1/1

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N2 - In this paper, we determine the optical refractive indices of different molarities of glucose using nano-laminated gold/chromium (Au-Cr) thin film via Kretschmann-based Surface Plasmon Resonance (K-SPR) sensing with angular interrogation. The nano-laminated Au-Cr K-SPR sensor detects the glucose presence in low- and high-concentration of 4-12 mmol/L and 55-277 mmol/L, respectively, under the exposure of 670 nm and 785 nm optical wavelengths. The experimental results showed that the minimum limit of detection (LOD) of Au-Cr K-SPR is 4 mmol/L and the glucose sensor sensitivities are in average of 3.41 o/M and 2.73o/M at 670 nm and 785 nm optical wavelength, respectively. Stable sensitivity for each concentration also shown from the sensorgram results, indicates the stable performance of nanolaminated Au-Cr SPR sensor to detect glucose in the range from mmol/L up to dmol/L. Values of refractive indices for glucose molarities obtained are 1.33187 (4 mmol/L) and 1.3191 (4 mmol/L) at 670 and 785 nm wavelength, respectively. These RI values are beneficial for numerical simulation of glucose sensors using nano-laminated Au-Cr thin films which have been reported for the first time. The sensor can be eventually deployed in integrated photonic sensing devices comprising of multiple analyte detection for lab-on-chip (LoC) and point-of care (PoC) applications.

AB - In this paper, we determine the optical refractive indices of different molarities of glucose using nano-laminated gold/chromium (Au-Cr) thin film via Kretschmann-based Surface Plasmon Resonance (K-SPR) sensing with angular interrogation. The nano-laminated Au-Cr K-SPR sensor detects the glucose presence in low- and high-concentration of 4-12 mmol/L and 55-277 mmol/L, respectively, under the exposure of 670 nm and 785 nm optical wavelengths. The experimental results showed that the minimum limit of detection (LOD) of Au-Cr K-SPR is 4 mmol/L and the glucose sensor sensitivities are in average of 3.41 o/M and 2.73o/M at 670 nm and 785 nm optical wavelength, respectively. Stable sensitivity for each concentration also shown from the sensorgram results, indicates the stable performance of nanolaminated Au-Cr SPR sensor to detect glucose in the range from mmol/L up to dmol/L. Values of refractive indices for glucose molarities obtained are 1.33187 (4 mmol/L) and 1.3191 (4 mmol/L) at 670 and 785 nm wavelength, respectively. These RI values are beneficial for numerical simulation of glucose sensors using nano-laminated Au-Cr thin films which have been reported for the first time. The sensor can be eventually deployed in integrated photonic sensing devices comprising of multiple analyte detection for lab-on-chip (LoC) and point-of care (PoC) applications.

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KW - Nano-laminated

KW - Refractive index

KW - Surface plasmon resonance

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