Reduced red-cell folate in mania

C. I. Hasanah, U. A. Khan, M. Musalmah, S. M. Razali

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

Forty-five hospitalised patients with DSM-III-R diagnosis of mania, were found to have a mean red-cell folate level of 193 nmol/1, as compared to 896 nmol/1 in the control group (P < 0.00001). Assessment of serum folate in both groups showed no significant difference in the levels. Furthermore the manic patients and the controls were matched by the socio-economic status. This indicated that the reduced red-cell folate in mania is associated with the illness and not due to reduced absorption or dietary deficiency of folate. Considering previous studies that showed reduced red-cell folate in depression, our findings suggest that reduced red-cell folate occurred in both phases of bipolar disorders.

Original languageEnglish
Pages (from-to)95-99
Number of pages5
JournalJournal of Affective Disorders
Volume46
Issue number2
DOIs
Publication statusPublished - 1 Nov 1997
Externally publishedYes

Fingerprint

Bipolar Disorder
Folic Acid
Diagnostic and Statistical Manual of Mental Disorders
Economics
Depression
Control Groups
Serum

Keywords

  • Mania
  • Red-cell folate
  • Serum folate

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Behavioral Neuroscience
  • Biological Psychiatry
  • Neurology
  • Psychology(all)

Cite this

Hasanah, C. I., Khan, U. A., Musalmah, M., & Razali, S. M. (1997). Reduced red-cell folate in mania. Journal of Affective Disorders, 46(2), 95-99. https://doi.org/10.1016/S0165-0327(97)00096-7

Reduced red-cell folate in mania. / Hasanah, C. I.; Khan, U. A.; Musalmah, M.; Razali, S. M.

In: Journal of Affective Disorders, Vol. 46, No. 2, 01.11.1997, p. 95-99.

Research output: Contribution to journalArticle

Hasanah, CI, Khan, UA, Musalmah, M & Razali, SM 1997, 'Reduced red-cell folate in mania', Journal of Affective Disorders, vol. 46, no. 2, pp. 95-99. https://doi.org/10.1016/S0165-0327(97)00096-7
Hasanah CI, Khan UA, Musalmah M, Razali SM. Reduced red-cell folate in mania. Journal of Affective Disorders. 1997 Nov 1;46(2):95-99. https://doi.org/10.1016/S0165-0327(97)00096-7
Hasanah, C. I. ; Khan, U. A. ; Musalmah, M. ; Razali, S. M. / Reduced red-cell folate in mania. In: Journal of Affective Disorders. 1997 ; Vol. 46, No. 2. pp. 95-99.
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