Recurrence of a nasopharyngeal carcinoma manifesting as a cerebellopontine angle mass

Min Han Kong, Jahendran Jeevanan, Jegan Thanabalan

Research output: Contribution to journalArticle

Abstract

As many as 31% of patients with nasopharyngeal carcinoma present with intracranial extension. Despite this high percentage, extension to the cerebellopontine angle is rare. The mechanism of tumor spread to the cerebellopontine angle is not completely understood. The most likely mechanism is direct extension to the skull base with involvement of the petrous apex and further extension posteriorly via the medial tentorial edge. We report the case of a 46-year-old woman with nasopharyngeal carcinoma who had been treated initially with chemoradiation and subsequently with stereotactic radiosurgery for residual tumor. One year later, she presented with an intracranial recurrence of the nasopharyngeal carcinoma in the cerebellopontine angle; the recurrence mimicked a benign tumor on magnetic resonance imaging. The tumor was ultimately diagnosed as an undifferentiated carcinoma of nasopharyngeal origin. She was treated with palliative chemotherapy.

Original languageEnglish
JournalEar, Nose and Throat Journal
Volume92
Issue number12
Publication statusPublished - 2013

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Cerebellopontine Angle
Recurrence
Neoplasms
Radiosurgery
Skull Base
Residual Neoplasm
Magnetic Resonance Imaging
Carcinoma
Drug Therapy
Nasopharyngeal carcinoma

ASJC Scopus subject areas

  • Otorhinolaryngology

Cite this

Recurrence of a nasopharyngeal carcinoma manifesting as a cerebellopontine angle mass. / Kong, Min Han; Jeevanan, Jahendran; Thanabalan, Jegan.

In: Ear, Nose and Throat Journal, Vol. 92, No. 12, 2013.

Research output: Contribution to journalArticle

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