Recent advances in the discovery and development of stilbenes and lactones in anticancer therapy

Salmaan H. Inayat-Hussain, Noel F. Thomas

    Research output: Contribution to journalArticle

    19 Citations (Scopus)

    Abstract

    The stilbene and lactone moieties are important components of a number of compounds that have potential therapeutic roles in many areas including anticancer therapy. Since the significance of these moieties were recognised, a myriad of structurally-related or different analogues have been studied and tested against various pharmacological modalities that may provide novel targets in therapies, for example in conditions where insufficient apoptosis leads to the formation of cancer. Recently, there have been a number of studies directed at the search for novel anticancer compounds incorporating stilbene and/or lactone moieties. The particular aim of this review is to focus on, and summarise, selected patents from 1999 - 2003 on stilbenes and lactones with anticancer properties. 2004

    Original languageEnglish
    Pages (from-to)819-835
    Number of pages17
    JournalExpert Opinion on Therapeutic Patents
    Volume14
    Issue number6
    DOIs
    Publication statusPublished - Jun 2004

    Fingerprint

    Stilbenes
    Lactones
    patent
    cancer
    Patents
    Therapeutics
    Pharmacology
    Apoptosis
    Neoplasms

    Keywords

    • Anticancer
    • Apoptosis
    • Combretastatin
    • Lactone
    • Rapamycin
    • Stilbene

    ASJC Scopus subject areas

    • Medicine (miscellaneous)
    • Pharmacology
    • Law

    Cite this

    Recent advances in the discovery and development of stilbenes and lactones in anticancer therapy. / Inayat-Hussain, Salmaan H.; Thomas, Noel F.

    In: Expert Opinion on Therapeutic Patents, Vol. 14, No. 6, 06.2004, p. 819-835.

    Research output: Contribution to journalArticle

    Inayat-Hussain, Salmaan H. ; Thomas, Noel F. / Recent advances in the discovery and development of stilbenes and lactones in anticancer therapy. In: Expert Opinion on Therapeutic Patents. 2004 ; Vol. 14, No. 6. pp. 819-835.
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