Quality of life in patients with neovascular age related macular degeneration (n-AMD) seen in a public hospital of Malaysia

Rituparna Ghoshal, Sharanjeet Kaur Malkeet Singh, Norliza Mohamad Fadzil, Somnath Ghosh, Norfariza Ngah, Roslin Azni Binti Abd Aziz

Research output: Contribution to journalArticle

Abstract

The purpose of the present study was to assess quality of life (QOL) in n-AMD patients seen in a Malaysian public hospital and to further identify visual and demographic factors that may contribute to QOL scores of these patients. Patients with any form of n-AMD in at least one eye were recruited from hospital’s ophthalmology department. Bahasa Malaysia version of National Eye Institute Visual function questionnaire-25 (NEI-VFQ-25) was administered to all participants. Demographics, visual functions (VF) including best corrected distance visual acuity (BCDVA), contrast sensitivity (CS), near visual acuity (NVA) and reading speed (RS) were recorded. Eighty-six patients (Malay=26, Indian=23, Chinese=37) aged 52 to 85 years, diagnosed with n-AMD were chosen to participate. Their mean NEI-VFQ composite score (NEI-VFQ CS) was 66.91 ± 13.07. However, no significant difference in NEI-VFQ CS between gender, races and between the two sub groups of n-AMD were observed (p>0.05). NEI-VFQ CS showed a significant association with RS (correlation coefficient (ρ) =0.627), NVA (ρ = -.660), BCDVA (ρ = -.586), CS (ρ =.0.515). A linear model showed that a combination of BCDVA, NVA, CS is accounted for a significant 38 % variability of NEI-VFQ CS (R2 =0.382, p<0.001). In conclusion, the QOL of Malaysian n-AMD patients were found to be low. Thus, the study results indicated the need of developing necessary management strategies to address this QOL issues in n-AMD patients in Malaysia. Furthermore, the present study suggested incorporating appropriate VF such as near acuity, contrast sensitivity, reading speed in clinical settings while assessing n-AMD patients as these VF explain the patient’s perception about the impact of this disease.

Original languageEnglish
Pages (from-to)2447-2454
Number of pages8
JournalSains Malaysiana
Volume47
Issue number10
DOIs
Publication statusPublished - 1 Oct 2018

Fingerprint

Public Hospitals
Malaysia
Macular Degeneration
Quality of Life
Visual Acuity
Contrast Sensitivity
Reading
National Eye Institute (U.S.)
Demography
Hospital Departments
Ophthalmology
Linear Models

Keywords

  • Neovascular AMD (n-AMD)
  • Vision targeted quality of life (VTQOL)
  • Visual functions (VF)

ASJC Scopus subject areas

  • General

Cite this

Quality of life in patients with neovascular age related macular degeneration (n-AMD) seen in a public hospital of Malaysia. / Ghoshal, Rituparna; Malkeet Singh, Sharanjeet Kaur; Mohamad Fadzil, Norliza; Ghosh, Somnath; Ngah, Norfariza; Aziz, Roslin Azni Binti Abd.

In: Sains Malaysiana, Vol. 47, No. 10, 01.10.2018, p. 2447-2454.

Research output: Contribution to journalArticle

Ghoshal, Rituparna ; Malkeet Singh, Sharanjeet Kaur ; Mohamad Fadzil, Norliza ; Ghosh, Somnath ; Ngah, Norfariza ; Aziz, Roslin Azni Binti Abd. / Quality of life in patients with neovascular age related macular degeneration (n-AMD) seen in a public hospital of Malaysia. In: Sains Malaysiana. 2018 ; Vol. 47, No. 10. pp. 2447-2454.
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