Quality of life and recurrence of disease in patients with eosinophilic and non-eosinophilic chronic rhinosinusitis with nasal polyposis

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Abstract

Objective: To assess the quality of life (QoL) and recurrence of disease in patients with eosinophilic (ECRSwNP) and non-eosinophilic chronic rhinosinusitis with nasal polyposis (non-ECRSwNP) post endoscopic sinus surgery (ESS). Methodology: A cross-sectional comparative study was carried out in the Otorhinolaryngology – HNS Department, Universiti Kebangsaan Malaysia Medical Center (UKMMC). Subjective assessments of nasal symptoms and quality of life (QoL) using SNOT-22 and Visual Analogue Scale (VAS) and objective endoscopic assessment was undertaken using a modified Hadley endoscopic examination. Results: There was no significant statistical difference in the quality of life between the ECRSwNP and non-ECRSwNP groups as evidenced by the SNOT-22 score and the VAS comparison (p>0.05). However, there was a significant difference in terms of recurrence of disease with the presence of nasal polyps on endoscopic examination. (p = 0.016) Conclusion: In conclusion, we found that there is no significant difference in QoL between ECRSwNP and non-ECRSwNP. There is higher frequency of recurrence of nasal polyps amongst ECRSwNP.

Original languageEnglish
Pages (from-to)1-6
Number of pages6
JournalMedical Journal of Malaysia
Volume73
Issue number1
Publication statusPublished - 1 Feb 2018

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Nose
Quality of Life
Nasal Polyps
Recurrence
Visual Analog Scale
Symptom Assessment
Malaysia
Otolaryngology
Cross-Sectional Studies

Keywords

  • CRSwNP
  • Eosinophilic
  • Polyps
  • QoL
  • SNOT 22

ASJC Scopus subject areas

  • Medicine(all)

Cite this

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title = "Quality of life and recurrence of disease in patients with eosinophilic and non-eosinophilic chronic rhinosinusitis with nasal polyposis",
abstract = "Objective: To assess the quality of life (QoL) and recurrence of disease in patients with eosinophilic (ECRSwNP) and non-eosinophilic chronic rhinosinusitis with nasal polyposis (non-ECRSwNP) post endoscopic sinus surgery (ESS). Methodology: A cross-sectional comparative study was carried out in the Otorhinolaryngology – HNS Department, Universiti Kebangsaan Malaysia Medical Center (UKMMC). Subjective assessments of nasal symptoms and quality of life (QoL) using SNOT-22 and Visual Analogue Scale (VAS) and objective endoscopic assessment was undertaken using a modified Hadley endoscopic examination. Results: There was no significant statistical difference in the quality of life between the ECRSwNP and non-ECRSwNP groups as evidenced by the SNOT-22 score and the VAS comparison (p>0.05). However, there was a significant difference in terms of recurrence of disease with the presence of nasal polyps on endoscopic examination. (p = 0.016) Conclusion: In conclusion, we found that there is no significant difference in QoL between ECRSwNP and non-ECRSwNP. There is higher frequency of recurrence of nasal polyps amongst ECRSwNP.",
keywords = "CRSwNP, Eosinophilic, Polyps, QoL, SNOT 22",
author = "Husain, {Nor Khairina} and Salina Husain and Gendeh, {Balwant Singh} and {Wan Hamizan}, {Aneeza Khairiyah} and Valerie Lund",
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AU - Wan Hamizan, Aneeza Khairiyah

AU - Lund, Valerie

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N2 - Objective: To assess the quality of life (QoL) and recurrence of disease in patients with eosinophilic (ECRSwNP) and non-eosinophilic chronic rhinosinusitis with nasal polyposis (non-ECRSwNP) post endoscopic sinus surgery (ESS). Methodology: A cross-sectional comparative study was carried out in the Otorhinolaryngology – HNS Department, Universiti Kebangsaan Malaysia Medical Center (UKMMC). Subjective assessments of nasal symptoms and quality of life (QoL) using SNOT-22 and Visual Analogue Scale (VAS) and objective endoscopic assessment was undertaken using a modified Hadley endoscopic examination. Results: There was no significant statistical difference in the quality of life between the ECRSwNP and non-ECRSwNP groups as evidenced by the SNOT-22 score and the VAS comparison (p>0.05). However, there was a significant difference in terms of recurrence of disease with the presence of nasal polyps on endoscopic examination. (p = 0.016) Conclusion: In conclusion, we found that there is no significant difference in QoL between ECRSwNP and non-ECRSwNP. There is higher frequency of recurrence of nasal polyps amongst ECRSwNP.

AB - Objective: To assess the quality of life (QoL) and recurrence of disease in patients with eosinophilic (ECRSwNP) and non-eosinophilic chronic rhinosinusitis with nasal polyposis (non-ECRSwNP) post endoscopic sinus surgery (ESS). Methodology: A cross-sectional comparative study was carried out in the Otorhinolaryngology – HNS Department, Universiti Kebangsaan Malaysia Medical Center (UKMMC). Subjective assessments of nasal symptoms and quality of life (QoL) using SNOT-22 and Visual Analogue Scale (VAS) and objective endoscopic assessment was undertaken using a modified Hadley endoscopic examination. Results: There was no significant statistical difference in the quality of life between the ECRSwNP and non-ECRSwNP groups as evidenced by the SNOT-22 score and the VAS comparison (p>0.05). However, there was a significant difference in terms of recurrence of disease with the presence of nasal polyps on endoscopic examination. (p = 0.016) Conclusion: In conclusion, we found that there is no significant difference in QoL between ECRSwNP and non-ECRSwNP. There is higher frequency of recurrence of nasal polyps amongst ECRSwNP.

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