Psychological distress, quality of life and coping in cancer patients

A prospective study

Ariaratnam Suthahar, K. Gurpreet, D. Ambigga, S. Dhachayani, Fuad Ismail, T. Maniam, C. B. Osman, O. Ainsah

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

We present the results and conclusions of an observational prospective cohort design study using self-administered questionnaires to determine correlation between psychosocial factors and cancer outcome among 80 consecutive newly diagnosed treatment naïve cancer subjects who were being referred to the Oncology Clinic, Hospital Universiti Kebangsaan Malaysia. Subjects were recruited over a period of 43 weeks from October 2000 till July 2001. Follow-up assessments were carried out at 6-months and 12 to 26 months later. The prediction of survival time was performed by the Cox Regression Analysis method with adjustments for biological and psychosocial risk factors. It was noted that depression (p = 0.001), stage 4 cancer disease (p = 0.016), neurological (p = 0.032), gastrointestinal tract (p = 0.04), head and neck (p = 0.011), gynaecological (p = 0.005) and bone and soft tissue (p = 0.030) malignancies were independent and statistically significant prognostic factor of survival during the study period. It was further shown than depressed patients were found to have almost four fold greater risk of dying than non-depressed patients and patients with stage 4 cancer illness have a five fold greater risk of dying than patients with stage 1 disease. Furthermore, based on tumour types subjects with neurological, gynaecological, head and neck, bone and soft tissue and gastro intestinal tract malignancies were found to have approximately thirty-six, twenty-five, twenty-two, sixteen and seven fold greater risk of dying respectively when compared to subjects with genitourinary cancers. This study further affirms the need for health care providers to be aware of the psychological aspects of the cancer patient and provide appropriate therapy so as to ensure that this group of individuals would have enhanced survival rates.

Original languageEnglish
Pages (from-to)362-368
Number of pages7
JournalMedical Journal of Malaysia
Volume63
Issue number5
Publication statusPublished - Dec 2008

Fingerprint

Quality of Life
Prospective Studies
Psychology
Neoplasms
Neck
Head
Urogenital Neoplasms
Bone and Bones
Survival
Malaysia
Health Personnel
Gastrointestinal Tract
Cohort Studies
Survival Rate
Regression Analysis
Depression
Therapeutics

Keywords

  • Cancer patients
  • Cox regression analyst
  • Depression
  • Survival

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Suthahar, A., Gurpreet, K., Ambigga, D., Dhachayani, S., Ismail, F., Maniam, T., ... Ainsah, O. (2008). Psychological distress, quality of life and coping in cancer patients: A prospective study. Medical Journal of Malaysia, 63(5), 362-368.

Psychological distress, quality of life and coping in cancer patients : A prospective study. / Suthahar, Ariaratnam; Gurpreet, K.; Ambigga, D.; Dhachayani, S.; Ismail, Fuad; Maniam, T.; Osman, C. B.; Ainsah, O.

In: Medical Journal of Malaysia, Vol. 63, No. 5, 12.2008, p. 362-368.

Research output: Contribution to journalArticle

Suthahar, A, Gurpreet, K, Ambigga, D, Dhachayani, S, Ismail, F, Maniam, T, Osman, CB & Ainsah, O 2008, 'Psychological distress, quality of life and coping in cancer patients: A prospective study', Medical Journal of Malaysia, vol. 63, no. 5, pp. 362-368.
Suthahar A, Gurpreet K, Ambigga D, Dhachayani S, Ismail F, Maniam T et al. Psychological distress, quality of life and coping in cancer patients: A prospective study. Medical Journal of Malaysia. 2008 Dec;63(5):362-368.
Suthahar, Ariaratnam ; Gurpreet, K. ; Ambigga, D. ; Dhachayani, S. ; Ismail, Fuad ; Maniam, T. ; Osman, C. B. ; Ainsah, O. / Psychological distress, quality of life and coping in cancer patients : A prospective study. In: Medical Journal of Malaysia. 2008 ; Vol. 63, No. 5. pp. 362-368.
@article{2b23b28370954ec6aa2f463234c6e042,
title = "Psychological distress, quality of life and coping in cancer patients: A prospective study",
abstract = "We present the results and conclusions of an observational prospective cohort design study using self-administered questionnaires to determine correlation between psychosocial factors and cancer outcome among 80 consecutive newly diagnosed treatment na{\"i}ve cancer subjects who were being referred to the Oncology Clinic, Hospital Universiti Kebangsaan Malaysia. Subjects were recruited over a period of 43 weeks from October 2000 till July 2001. Follow-up assessments were carried out at 6-months and 12 to 26 months later. The prediction of survival time was performed by the Cox Regression Analysis method with adjustments for biological and psychosocial risk factors. It was noted that depression (p = 0.001), stage 4 cancer disease (p = 0.016), neurological (p = 0.032), gastrointestinal tract (p = 0.04), head and neck (p = 0.011), gynaecological (p = 0.005) and bone and soft tissue (p = 0.030) malignancies were independent and statistically significant prognostic factor of survival during the study period. It was further shown than depressed patients were found to have almost four fold greater risk of dying than non-depressed patients and patients with stage 4 cancer illness have a five fold greater risk of dying than patients with stage 1 disease. Furthermore, based on tumour types subjects with neurological, gynaecological, head and neck, bone and soft tissue and gastro intestinal tract malignancies were found to have approximately thirty-six, twenty-five, twenty-two, sixteen and seven fold greater risk of dying respectively when compared to subjects with genitourinary cancers. This study further affirms the need for health care providers to be aware of the psychological aspects of the cancer patient and provide appropriate therapy so as to ensure that this group of individuals would have enhanced survival rates.",
keywords = "Cancer patients, Cox regression analyst, Depression, Survival",
author = "Ariaratnam Suthahar and K. Gurpreet and D. Ambigga and S. Dhachayani and Fuad Ismail and T. Maniam and Osman, {C. B.} and O. Ainsah",
year = "2008",
month = "12",
language = "English",
volume = "63",
pages = "362--368",
journal = "Medical Journal of Malaysia",
issn = "0300-5283",
publisher = "Malaysian Medical Association",
number = "5",

}

TY - JOUR

T1 - Psychological distress, quality of life and coping in cancer patients

T2 - A prospective study

AU - Suthahar, Ariaratnam

AU - Gurpreet, K.

AU - Ambigga, D.

AU - Dhachayani, S.

AU - Ismail, Fuad

AU - Maniam, T.

AU - Osman, C. B.

AU - Ainsah, O.

PY - 2008/12

Y1 - 2008/12

N2 - We present the results and conclusions of an observational prospective cohort design study using self-administered questionnaires to determine correlation between psychosocial factors and cancer outcome among 80 consecutive newly diagnosed treatment naïve cancer subjects who were being referred to the Oncology Clinic, Hospital Universiti Kebangsaan Malaysia. Subjects were recruited over a period of 43 weeks from October 2000 till July 2001. Follow-up assessments were carried out at 6-months and 12 to 26 months later. The prediction of survival time was performed by the Cox Regression Analysis method with adjustments for biological and psychosocial risk factors. It was noted that depression (p = 0.001), stage 4 cancer disease (p = 0.016), neurological (p = 0.032), gastrointestinal tract (p = 0.04), head and neck (p = 0.011), gynaecological (p = 0.005) and bone and soft tissue (p = 0.030) malignancies were independent and statistically significant prognostic factor of survival during the study period. It was further shown than depressed patients were found to have almost four fold greater risk of dying than non-depressed patients and patients with stage 4 cancer illness have a five fold greater risk of dying than patients with stage 1 disease. Furthermore, based on tumour types subjects with neurological, gynaecological, head and neck, bone and soft tissue and gastro intestinal tract malignancies were found to have approximately thirty-six, twenty-five, twenty-two, sixteen and seven fold greater risk of dying respectively when compared to subjects with genitourinary cancers. This study further affirms the need for health care providers to be aware of the psychological aspects of the cancer patient and provide appropriate therapy so as to ensure that this group of individuals would have enhanced survival rates.

AB - We present the results and conclusions of an observational prospective cohort design study using self-administered questionnaires to determine correlation between psychosocial factors and cancer outcome among 80 consecutive newly diagnosed treatment naïve cancer subjects who were being referred to the Oncology Clinic, Hospital Universiti Kebangsaan Malaysia. Subjects were recruited over a period of 43 weeks from October 2000 till July 2001. Follow-up assessments were carried out at 6-months and 12 to 26 months later. The prediction of survival time was performed by the Cox Regression Analysis method with adjustments for biological and psychosocial risk factors. It was noted that depression (p = 0.001), stage 4 cancer disease (p = 0.016), neurological (p = 0.032), gastrointestinal tract (p = 0.04), head and neck (p = 0.011), gynaecological (p = 0.005) and bone and soft tissue (p = 0.030) malignancies were independent and statistically significant prognostic factor of survival during the study period. It was further shown than depressed patients were found to have almost four fold greater risk of dying than non-depressed patients and patients with stage 4 cancer illness have a five fold greater risk of dying than patients with stage 1 disease. Furthermore, based on tumour types subjects with neurological, gynaecological, head and neck, bone and soft tissue and gastro intestinal tract malignancies were found to have approximately thirty-six, twenty-five, twenty-two, sixteen and seven fold greater risk of dying respectively when compared to subjects with genitourinary cancers. This study further affirms the need for health care providers to be aware of the psychological aspects of the cancer patient and provide appropriate therapy so as to ensure that this group of individuals would have enhanced survival rates.

KW - Cancer patients

KW - Cox regression analyst

KW - Depression

KW - Survival

UR - http://www.scopus.com/inward/record.url?scp=60849127605&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=60849127605&partnerID=8YFLogxK

M3 - Article

VL - 63

SP - 362

EP - 368

JO - Medical Journal of Malaysia

JF - Medical Journal of Malaysia

SN - 0300-5283

IS - 5

ER -