Protective effect of apple mangrove Sonneratia caseolaris extract in Edwardsiella tarda-infected African catfish, Clarias gariepinus

Alia Syafiqah Aznan, Kok Leong Lee, Low Chen Fei, Nurul Aqilah Iberahim, Wan Nurhafizah Wan Ibrahim, Nadirah Musa, Yik Sung Yeong, Najiah Musa

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Outbreaks of edwardsiellosis have severe impact on the aquaculture production of African catfish Clarias gariepinus. In this study, feed supplemented with apple mangrove Sonneratia caseolaris extract was evaluated for its protective effect against Edwardsiella tarda infection in African catfish. Results showed an increase in growth performance and higher survival rate in the treatment groups in a dose dependent manner. Haematological analyses showed an increase in white blood cell count in the treatment groups. Histopathological analysis revealed degenerative changes and regeneration of liver tissue architecture in both the control and treatment groups. However, the presence of inflammatory cells was found exclusively in the kidney of T3 treatment group that was supplemented with the highest dose of extract at 3.17 mg/ml, which inferred the activation of immune response in the fish. Contrast to the deteriorative alteration observed in the kidney of the control group due to E. tarda infection, treatment group exhibited tissue regeneration and well-defined kidney tissue architecture at 3 dpi. Taken together, these results demonstrated that supplementation with the methanol extract of S. caseolaris possesses protective effect in African catfish against the infection of E. tarda.

Original languageEnglish
Pages (from-to)338-345
Number of pages8
JournalFish and Shellfish Immunology
Volume78
DOIs
Publication statusPublished - 1 Jul 2018

Fingerprint

Edwardsiella tarda
Clarias gariepinus
catfish
mangrove
protective effect
apples
kidneys
Tissue
Aquaculture
Tissue regeneration
extracts
regeneration
infection
Liver
liver regeneration
Fish
aquaculture production
Methanol
Blood
Chemical activation

Keywords

  • African catfish
  • Bacterial infection
  • Edwardsiella tarda
  • Immunostimulant
  • Protective effect
  • Sonneratia caseolaris

ASJC Scopus subject areas

  • Environmental Chemistry
  • Aquatic Science

Cite this

Protective effect of apple mangrove Sonneratia caseolaris extract in Edwardsiella tarda-infected African catfish, Clarias gariepinus. / Aznan, Alia Syafiqah; Lee, Kok Leong; Chen Fei, Low; Iberahim, Nurul Aqilah; Wan Ibrahim, Wan Nurhafizah; Musa, Nadirah; Yeong, Yik Sung; Musa, Najiah.

In: Fish and Shellfish Immunology, Vol. 78, 01.07.2018, p. 338-345.

Research output: Contribution to journalArticle

Aznan, Alia Syafiqah ; Lee, Kok Leong ; Chen Fei, Low ; Iberahim, Nurul Aqilah ; Wan Ibrahim, Wan Nurhafizah ; Musa, Nadirah ; Yeong, Yik Sung ; Musa, Najiah. / Protective effect of apple mangrove Sonneratia caseolaris extract in Edwardsiella tarda-infected African catfish, Clarias gariepinus. In: Fish and Shellfish Immunology. 2018 ; Vol. 78. pp. 338-345.
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