Probiotics and Their Potential Preventive and Therapeutic Role for Cancer, High Serum Cholesterol, and Allergic and HIV Diseases

Yusuf Nazir, Syed Ammar Hussain, Aidil Abdul Hamid, Yuanda Song

Research output: Contribution to journalReview article

4 Citations (Scopus)

Abstract

The potential health benefits of probiotics have long been elucidated since Metchnikoff and his coworkers postulated the association of probiotic consumption on human's health and longevity. Since then, many scientific findings and research have further established the correlation of probiotic and gut-associated diseases such as irritable bowel disease and chronic and antibiotic-associated diarrhea. However, the beneficial impact of probiotic is not limited to the gut-associated diseases alone, but also in different acute and chronic infectious diseases. This is due to the fact that probiotics are able to modify the intestinal microbial ecosystem, enhance the gut barrier function, provide competitive adherence to the mucosa and epithelium, produce antimicrobial substances, and modulate the immune activity by enhancing the innate and adaptive immune response. Nevertheless, the current literature with respect to the association of probiotic and cancer, high serum cholesterol, and allergic and HIV diseases are still scarce and controversial. Therefore, in the present work, we reviewed the potential preventive and therapeutic role of probiotics for cancer, high serum cholesterol, and allergic and HIV diseases as well as providing its possible mechanism of actions.

Original languageEnglish
Article number3428437
JournalBioMed Research International
Volume2018
DOIs
Publication statusPublished - 1 Jan 2018

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Probiotics
Cholesterol
HIV
Serum
Neoplasms
Therapeutics
Chronic Disease
Health
Adaptive Immunity
Insurance Benefits
Innate Immunity
Ecosystems
Communicable Diseases
Ecosystem
Diarrhea
Mucous Membrane
Epithelium
Anti-Bacterial Agents
Research

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Immunology and Microbiology(all)

Cite this

Probiotics and Their Potential Preventive and Therapeutic Role for Cancer, High Serum Cholesterol, and Allergic and HIV Diseases. / Nazir, Yusuf; Hussain, Syed Ammar; Abdul Hamid, Aidil; Song, Yuanda.

In: BioMed Research International, Vol. 2018, 3428437, 01.01.2018.

Research output: Contribution to journalReview article

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