Primary follicular lymphoma of the pancreas

A rare tumour mimicking pancreatic carcinoma

Sugunah Sallapan, Norzailin Abu Bakar, Razman Jarmin, Noraidah Masir, Fazarina Mohammed

Research output: Contribution to journalArticle

Abstract

Introduction: Primary pancreatic lymphomas are extremely rare. Clinically, primary pancreatic lymphoma mimics symptoms of carcinoma of the pancreatic head. Clinical and radiological features may overlap with other pancreatic conditions such as carcinoma, neuroendocrine tumours and autoimmune pancreatitis. Case Report: We report a case of a 75-year-old man who presented with symptoms of obstructive jaundice. Ultrasonography and computed tomography (CT) showed an ill-defined lobulated soft tissue lesion at the head/uncinate process of the pancreas measuring 4.5 × 4.9 × 5.8 cm. The patient underwent pancreaticoduodenectomy for suspected pancreatic head/uncinate process carcinoma. Histopathology and immunohistochemical assessment of the pancreatic lesion established the diagnosis of a low-grade follicular lymphoma. Discussion: Clinical and imaging features of primary pancreatic lymphoma may often overlap with pancreatic carcinoma. There is a value of obtaining preoperative tissue diagnosis such as tissue biopsy and fine needle aspiration (FNA) cytology with or without flow cytometry to make an accurate diagnosis of non-Hodgkin lymphoma and alleviate the need of more radical surgery in pancreatic lymphoma.

Original languageEnglish
Pages (from-to)359-371
Number of pages13
JournalMalaysian Journal of Pathology
Volume40
Issue number3
Publication statusPublished - 1 Dec 2018

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Follicular Lymphoma
Pancreas
Lymphoma
Non-Hodgkin's Lymphoma
Neoplasms
Carcinoma
Pancreaticoduodenectomy
Neuroendocrine Tumors
Obstructive Jaundice
Fine Needle Biopsy
Pancreatitis
Cell Biology
Ultrasonography
Flow Cytometry
Head
Tomography
Pancreatic Carcinoma

Keywords

  • Follicular lymphoma
  • Non-hodgkin lymphoma
  • Obstructive jaundice
  • Pancreas
  • Primary pancreatic lymphoma (PPL)

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Histology
  • Cell Biology

Cite this

Primary follicular lymphoma of the pancreas : A rare tumour mimicking pancreatic carcinoma. / Sallapan, Sugunah; Abu Bakar, Norzailin; Jarmin, Razman; Masir, Noraidah; Mohammed, Fazarina.

In: Malaysian Journal of Pathology, Vol. 40, No. 3, 01.12.2018, p. 359-371.

Research output: Contribution to journalArticle

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