Primary clear cell carcinoma of minor salivary gland of the soft palate: A case report

K. A. Saleh, Nurishmah Md Isa, Firouzeh, Bee See Goh

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Clear cells can be found in numerous salivary and non-salivary tumors in the head and neck region, including metastatic lesions. They are rare low-grade tumors accounting for less than 1% of all salivary gland tumors and occur almost exclusively in the intra-oral minor salivary glands. Hyalinizing clear cell carcinoma (HCCC) is an extremely rare and recently described neoplasm predominantly affecting the oral cavity. Histologically, it is characterized by nests of glycogen-rich monomorphic clear cells within a hyaline stroma. HCCC often follows an indolent course with a limited metastatic potential. It is therefore important to differentiate this entity from other more aggressive clear cell tumors including metastatic tumors such as renal cell carcinoma. We hereby report a case of HCCC localized in minor salivary glands specifically in soft palate for its rarity, as well as to discuss the role of immunohistochemical stains, essential for its definitive diagnosis.

Original languageEnglish
Pages (from-to)335-336
Number of pages2
JournalMedical Journal of Malaysia
Volume67
Issue number3
Publication statusPublished - Jun 2012

Fingerprint

Minor Salivary Glands
Soft Palate
Carcinoma
Neoplasms
Hyalin
Glandular and Epithelial Neoplasms
Glycogen
Renal Cell Carcinoma
Mouth
Coloring Agents
Neck
Head

Keywords

  • Hyalinizing clear cell carcinoma
  • Immunohistochemistry
  • Salivary gland
  • Soft palate

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Primary clear cell carcinoma of minor salivary gland of the soft palate : A case report. / Saleh, K. A.; Isa, Nurishmah Md; Firouzeh, ; Goh, Bee See.

In: Medical Journal of Malaysia, Vol. 67, No. 3, 06.2012, p. 335-336.

Research output: Contribution to journalArticle

Saleh, K. A. ; Isa, Nurishmah Md ; Firouzeh, ; Goh, Bee See. / Primary clear cell carcinoma of minor salivary gland of the soft palate : A case report. In: Medical Journal of Malaysia. 2012 ; Vol. 67, No. 3. pp. 335-336.
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