Primary biliary cirrhosis and auto immune hepatitis overlap syndrome mimicking cholangiocarcinoma

A. Adel, Zamri Zuhdi, Azlanudin Azman, J. J. Bong

Research output: Contribution to journalArticle

Abstract

Primary Biliary Cirrhosis (PBC) and Auto Immune Hepatitis (AIH) are autoimmune diseases of the liver which highlighted with slow destructive process of intra hepatic small bile ducts. As a result of these damages cholestasis and over the time tissue damage will happen, which leads to scarring, fibrosis and finally cirrhosis. Some patients may present with clinical and biochemical features of both conditions, which is called "Overlap syndrome". Here we are reporting a case of PBC-AIH overlap syndrome that primarily diagnosed as gallbladder carcinoma and went under operation and finally histological examination revealed to be PBC.

Original languageEnglish
JournalClinica Terapeutica
Volume164
Issue number6 SUPPL
DOIs
Publication statusPublished - 2014

Fingerprint

Cholangiocarcinoma
Biliary Liver Cirrhosis
Hepatitis
Fibrosis
Liver
Cholestasis
Bile Ducts
Gallbladder
Autoimmune Diseases
Cicatrix
Carcinoma

Keywords

  • Auto immune hepatitis
  • cholestasis overlap syndrome
  • Primary biliary cirrhosis

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Primary biliary cirrhosis and auto immune hepatitis overlap syndrome mimicking cholangiocarcinoma. / Adel, A.; Zuhdi, Zamri; Azman, Azlanudin; Bong, J. J.

In: Clinica Terapeutica, Vol. 164, No. 6 SUPPL, 2014.

Research output: Contribution to journalArticle

@article{06e59b11d38a44ceaf4925493e61284a,
title = "Primary biliary cirrhosis and auto immune hepatitis overlap syndrome mimicking cholangiocarcinoma",
abstract = "Primary Biliary Cirrhosis (PBC) and Auto Immune Hepatitis (AIH) are autoimmune diseases of the liver which highlighted with slow destructive process of intra hepatic small bile ducts. As a result of these damages cholestasis and over the time tissue damage will happen, which leads to scarring, fibrosis and finally cirrhosis. Some patients may present with clinical and biochemical features of both conditions, which is called {"}Overlap syndrome{"}. Here we are reporting a case of PBC-AIH overlap syndrome that primarily diagnosed as gallbladder carcinoma and went under operation and finally histological examination revealed to be PBC.",
keywords = "Auto immune hepatitis, cholestasis overlap syndrome, Primary biliary cirrhosis",
author = "A. Adel and Zamri Zuhdi and Azlanudin Azman and Bong, {J. J.}",
year = "2014",
doi = "10.7417/CT.2013.1643",
language = "English",
volume = "164",
journal = "Clinica Terapeutica",
issn = "0009-9074",
publisher = "Societa Editrice Universo",
number = "6 SUPPL",

}

TY - JOUR

T1 - Primary biliary cirrhosis and auto immune hepatitis overlap syndrome mimicking cholangiocarcinoma

AU - Adel, A.

AU - Zuhdi, Zamri

AU - Azman, Azlanudin

AU - Bong, J. J.

PY - 2014

Y1 - 2014

N2 - Primary Biliary Cirrhosis (PBC) and Auto Immune Hepatitis (AIH) are autoimmune diseases of the liver which highlighted with slow destructive process of intra hepatic small bile ducts. As a result of these damages cholestasis and over the time tissue damage will happen, which leads to scarring, fibrosis and finally cirrhosis. Some patients may present with clinical and biochemical features of both conditions, which is called "Overlap syndrome". Here we are reporting a case of PBC-AIH overlap syndrome that primarily diagnosed as gallbladder carcinoma and went under operation and finally histological examination revealed to be PBC.

AB - Primary Biliary Cirrhosis (PBC) and Auto Immune Hepatitis (AIH) are autoimmune diseases of the liver which highlighted with slow destructive process of intra hepatic small bile ducts. As a result of these damages cholestasis and over the time tissue damage will happen, which leads to scarring, fibrosis and finally cirrhosis. Some patients may present with clinical and biochemical features of both conditions, which is called "Overlap syndrome". Here we are reporting a case of PBC-AIH overlap syndrome that primarily diagnosed as gallbladder carcinoma and went under operation and finally histological examination revealed to be PBC.

KW - Auto immune hepatitis

KW - cholestasis overlap syndrome

KW - Primary biliary cirrhosis

UR - http://www.scopus.com/inward/record.url?scp=84896261783&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84896261783&partnerID=8YFLogxK

U2 - 10.7417/CT.2013.1643

DO - 10.7417/CT.2013.1643

M3 - Article

C2 - 24424229

AN - SCOPUS:84896261783

VL - 164

JO - Clinica Terapeutica

JF - Clinica Terapeutica

SN - 0009-9074

IS - 6 SUPPL

ER -