Primary aldosteronism

From bench to bedside

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Primary aldosteronism is now thought to be the commonest potentially curable and specifically treatable form of hypertension. The detection of primary aldosteronism is of utmost importance not only because it provides an opportunity for a targeted treatment, but also because it has been demonstrated that patients with primary aldosteronism are more prone to cardiovascular events and target organ damage than essential hypertensives. Normalization of blood pressure and hypokalemia should not be the only goal of treatment. Normalization of circulating aldosterone or mineralocorticoid blockade is necessary to prevent aldosterone-induced tissue damage that occurs independent of blood pressure. This review will focus on the current understanding and comprehensive management review of primary aldosteronism, highlighting the new evidence that has become recently available.

Original languageEnglish
Pages (from-to)31-39
Number of pages9
JournalEndocrine
Volume41
Issue number1
DOIs
Publication statusPublished - Feb 2012

Fingerprint

Hyperaldosteronism
Aldosterone
Blood Pressure
Mineralocorticoids
Hypokalemia
Hypertension
Therapeutics

Keywords

  • Adrenal venous sampling
  • Aldosterone renin ratio
  • Bilateral adrenal hyperplasia
  • Familial hyperaldosteronism
  • Primary aldosteronism

ASJC Scopus subject areas

  • Endocrinology
  • Endocrinology, Diabetes and Metabolism

Cite this

Primary aldosteronism : From bench to bedside. / Sukor, Norlela.

In: Endocrine, Vol. 41, No. 1, 02.2012, p. 31-39.

Research output: Contribution to journalArticle

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