Prescribing trends of Statins in Scotland

A drug utilization study

Asadul Mazid Helali, James Mclay, Isa Naina Mohamed

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Statins are highly effective in managing hypercholesterolaemia in patients with or without chronic heart disease due to extensive evidence for safety, efficacy and cost effectiveness. Observational cross sectional retrospective cohort study was done in approximately 200 primary care practices in Scotland. Frequency, rates and time trends for statin prescriptions together with demographic data and the prescribing patterns for high dose simvastatin and newer statins in its place was measured. 63%, 27%, 5%, 4% and 1% patients were prescribed simvastatin, atorvastatin, pravastatin, rosuvastatin and fluvastatin respectively (n = 1,91370). Prevalence for individual statin as well as for all statin prescriptions, significantly increased (p<0.05). Except rosuvastatin the incidence of other statins prescription significantly decreased (p<0.05). The highest number of patients, 884 (24%) switched to atorvastatin from high dose simvastatin. Increase in prevalent use and decrease in incident use of statins, implies the diminished cardiovascular disease related mortality and subsequent increased life expectancy of patients with cardiovascular disease.

Original languageEnglish
Pages (from-to)401-409
Number of pages9
JournalBangladesh Journal of Pharmacology
Volume8
Issue number4
DOIs
Publication statusPublished - 2013

Fingerprint

Drug Utilization
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Scotland
Simvastatin
Prescriptions
fluvastatin
Cardiovascular Diseases
Pravastatin
Life Expectancy
Hypercholesterolemia
Cost-Benefit Analysis
Heart Diseases
Primary Health Care
Chronic Disease
Cohort Studies
Retrospective Studies
Demography
Safety
Mortality
Incidence

Keywords

  • Prescribing trend
  • Scotland
  • Statin

ASJC Scopus subject areas

  • Pharmacology

Cite this

Prescribing trends of Statins in Scotland : A drug utilization study. / Helali, Asadul Mazid; Mclay, James; Naina Mohamed, Isa.

In: Bangladesh Journal of Pharmacology, Vol. 8, No. 4, 2013, p. 401-409.

Research output: Contribution to journalArticle

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