Preparation and characterization of macroporous bioactive glass ceramic made via sol-gel route and powder sintering method

Syed Nuzul Fadzli Syed Adam, Roslinda Shamsudin, Siti Rohani Zainuddin, Banjuraizah Johar, Firuz Zainuddin

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

The purpose of this study was to prepare macroporous glass ceramic scaffold by sol-gel glass synthesis and powder sintering method. Sodium nitrate was added during sol-gel process to obtain glass ceramic with mol composition of 42.11% SiO2 - 18.42% CaO - 29.82% Na2O - 9.65% P2O5. The glass particles were found to be thermally stable above 900°C as indicated by TGA/DTA analysis. The dried glass particles obtained from sol-gel process were compacted and sintered at 1000°C for 3 h soaking time. Sintering crystallized the glass by 71.5% of crystallinity with tetracalcium catena-hexaphosphate (V) (Ca4(P6O19) as the main crystalline phase as revealed by XRD analysis. Although glass crystallized during sintering, it showed a good in vitro bioactivity as apatite-like layer were deposited on the glass ceramic surface when immersed in simulated body fluid (SBF) for 14 days. SEM analysis proved the macroporous structure formation with pore size ranges between 30 and 350 µm due to foaming effect which occurred during sintering. Besides that, the glass ceramic surface formed into vitrified-like due to fluxing effect during sintering thus affected the porosity and densification measurement done by Archimedes test. In conclusion, the presence of sodium oxide in sol-gel glass ceramic composition by 29.82 mol % with sintering temperature at 1000°C is able to produce bioactive and macroporous glass ceramic that potentially be used as medical scaffold material.

Original languageEnglish
Pages (from-to)1025-1031
Number of pages7
JournalSains Malaysiana
Volume47
Issue number5
DOIs
Publication statusPublished - 1 May 2018

Fingerprint

Bioactive glass
Glass ceramics
Sol-gels
Sintering
Powders
Glass
Scaffolds
Sol-gel process
Sodium
Body fluids
Apatite
Bioactivity
Chemical analysis
Densification
Differential thermal analysis
Pore size
Nitrates
Porosity
Crystalline materials
Scanning electron microscopy

Keywords

  • Glass ceramic
  • Macroporous
  • Powder sintering
  • Scaffold
  • Sol-gel

ASJC Scopus subject areas

  • General

Cite this

Preparation and characterization of macroporous bioactive glass ceramic made via sol-gel route and powder sintering method. / Syed Adam, Syed Nuzul Fadzli; Shamsudin, Roslinda; Zainuddin, Siti Rohani; Johar, Banjuraizah; Zainuddin, Firuz.

In: Sains Malaysiana, Vol. 47, No. 5, 01.05.2018, p. 1025-1031.

Research output: Contribution to journalArticle

Syed Adam, Syed Nuzul Fadzli ; Shamsudin, Roslinda ; Zainuddin, Siti Rohani ; Johar, Banjuraizah ; Zainuddin, Firuz. / Preparation and characterization of macroporous bioactive glass ceramic made via sol-gel route and powder sintering method. In: Sains Malaysiana. 2018 ; Vol. 47, No. 5. pp. 1025-1031.
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AU - Zainuddin, Firuz

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AB - The purpose of this study was to prepare macroporous glass ceramic scaffold by sol-gel glass synthesis and powder sintering method. Sodium nitrate was added during sol-gel process to obtain glass ceramic with mol composition of 42.11% SiO2 - 18.42% CaO - 29.82% Na2O - 9.65% P2O5. The glass particles were found to be thermally stable above 900°C as indicated by TGA/DTA analysis. The dried glass particles obtained from sol-gel process were compacted and sintered at 1000°C for 3 h soaking time. Sintering crystallized the glass by 71.5% of crystallinity with tetracalcium catena-hexaphosphate (V) (Ca4(P6O19) as the main crystalline phase as revealed by XRD analysis. Although glass crystallized during sintering, it showed a good in vitro bioactivity as apatite-like layer were deposited on the glass ceramic surface when immersed in simulated body fluid (SBF) for 14 days. SEM analysis proved the macroporous structure formation with pore size ranges between 30 and 350 µm due to foaming effect which occurred during sintering. Besides that, the glass ceramic surface formed into vitrified-like due to fluxing effect during sintering thus affected the porosity and densification measurement done by Archimedes test. In conclusion, the presence of sodium oxide in sol-gel glass ceramic composition by 29.82 mol % with sintering temperature at 1000°C is able to produce bioactive and macroporous glass ceramic that potentially be used as medical scaffold material.

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