Prenylated flavones from Artocarpus lanceifolius and their cytotoxic properties against P-388 cells

Iqbal Musthapa, Jalifah Latip, Hiromitsu Takayama, Lia D. Juliawaty, Euis H. Hakim, Yana M. Syah

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

New prenylated flavones, artoindonesianins Z-4 and Z-5, together with four known prenylated flavones, artonin E, 12-hydroxyartonin E, artobiloxanthone, and cycloartobiloxanthone, have been isolated from the methanol extract of the tree bark of Artocarpus lanceifolius. The structures of these compounds were determined on the basis of spectroscopic data, including UV, IR, 1D and 2D NMR, and mass spectra. The cytotoxic effect of the isolated compounds against murine leukemia P-388 cells is described.

Original languageEnglish
Pages (from-to)927-930
Number of pages4
JournalNatural Product Communications
Volume4
Issue number7
Publication statusPublished - 2009

Fingerprint

Artocarpus
Flavones
flavones
Plant Bark
leukemia
Methanol
cytotoxicity
Leukemia
bark
methanol
cells
mice
extracts

Keywords

  • Artocarpus lanceifolius
  • Artoindonesianins Z-4 and Z-5
  • Moraceae
  • Murine leukemia P-388 cells
  • Prenylated flavones

ASJC Scopus subject areas

  • Drug Discovery
  • Pharmacology
  • Complementary and alternative medicine
  • Plant Science

Cite this

Musthapa, I., Latip, J., Takayama, H., Juliawaty, L. D., Hakim, E. H., & Syah, Y. M. (2009). Prenylated flavones from Artocarpus lanceifolius and their cytotoxic properties against P-388 cells. Natural Product Communications, 4(7), 927-930.

Prenylated flavones from Artocarpus lanceifolius and their cytotoxic properties against P-388 cells. / Musthapa, Iqbal; Latip, Jalifah; Takayama, Hiromitsu; Juliawaty, Lia D.; Hakim, Euis H.; Syah, Yana M.

In: Natural Product Communications, Vol. 4, No. 7, 2009, p. 927-930.

Research output: Contribution to journalArticle

Musthapa, I, Latip, J, Takayama, H, Juliawaty, LD, Hakim, EH & Syah, YM 2009, 'Prenylated flavones from Artocarpus lanceifolius and their cytotoxic properties against P-388 cells', Natural Product Communications, vol. 4, no. 7, pp. 927-930.
Musthapa, Iqbal ; Latip, Jalifah ; Takayama, Hiromitsu ; Juliawaty, Lia D. ; Hakim, Euis H. ; Syah, Yana M. / Prenylated flavones from Artocarpus lanceifolius and their cytotoxic properties against P-388 cells. In: Natural Product Communications. 2009 ; Vol. 4, No. 7. pp. 927-930.
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