Predictors of intrauterine insemination success

Zainul Rashid Mohd. Razi, Fee Bee Ong, Mohd Hashim Omar, S. P. Ng, A. Nurshaireen, M. D. Rahimah, S. Mariam, M. Zolaidah, N. S M N Sharifah-Teh, A. Saniros, B. Hasnita

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Intrauterine insemination (IUI) remains a therapeutic option within means of the majority of infertile couples in Malaysia. Therefore additional information on predictors of IUI success in the local context would provide a more concrete basis for counseling patients on expectations and treatment options. A retrospective analysis of 297 couples who underwent 445 IUI cycles from Jan 2005-Mar 2006 was undertaken. Four fifths were Malay with a mean paternal and maternal age of 35.53±5.82 (range 24-59) and 33.02±4.69 (range 21-46) years respectively. Causes of infertility were idiopathic (50%), endometriosis (17%) and anovulation/polycystic ovarian syndrome (15%). Almost 10% were oligoastenoteratozoospermic with another 23% oligozoospermic or astenozoospermic. Combined male and female factors occurred in 26%. A pregnancy rate (PR) of 9.4% per cycle; 14.1% per couple with a cumulative PR of 36.7% per 4 cycles was achieved. Those who became pregnant were significantly younger (31.29±4.43 vs. 33.21±4.68 years, p=0.011) and had more follicles (13.95±9.72 vs. 11.43±6.67, p=0.029) at the time of insemination. PR depreciated with maternal age and semen quality. Maternal and paternal age was inversely correlated to the number of follicles recmited (r=-0.30, p<0.0005) and progressive sperm motility (r=-0.125, p=0.013) respectively.

Original languageEnglish
Pages (from-to)599-607
Number of pages9
JournalMedical Journal of Malaysia
Volume61
Issue number5
Publication statusPublished - Dec 2006

Fingerprint

Insemination
Maternal Age
Pregnancy Rate
Paternal Age
Anovulation
Mars
Semen Analysis
Sperm Motility
Polycystic Ovary Syndrome
Malaysia
Endometriosis
Infertility
Counseling
Therapeutics

Keywords

  • IUI success
  • Maternal age
  • Motile sperm count
  • Pregnancy rate

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Mohd. Razi, Z. R., Ong, F. B., Omar, M. H., Ng, S. P., Nurshaireen, A., Rahimah, M. D., ... Hasnita, B. (2006). Predictors of intrauterine insemination success. Medical Journal of Malaysia, 61(5), 599-607.

Predictors of intrauterine insemination success. / Mohd. Razi, Zainul Rashid; Ong, Fee Bee; Omar, Mohd Hashim; Ng, S. P.; Nurshaireen, A.; Rahimah, M. D.; Mariam, S.; Zolaidah, M.; Sharifah-Teh, N. S M N; Saniros, A.; Hasnita, B.

In: Medical Journal of Malaysia, Vol. 61, No. 5, 12.2006, p. 599-607.

Research output: Contribution to journalArticle

Mohd. Razi, ZR, Ong, FB, Omar, MH, Ng, SP, Nurshaireen, A, Rahimah, MD, Mariam, S, Zolaidah, M, Sharifah-Teh, NSMN, Saniros, A & Hasnita, B 2006, 'Predictors of intrauterine insemination success', Medical Journal of Malaysia, vol. 61, no. 5, pp. 599-607.
Mohd. Razi ZR, Ong FB, Omar MH, Ng SP, Nurshaireen A, Rahimah MD et al. Predictors of intrauterine insemination success. Medical Journal of Malaysia. 2006 Dec;61(5):599-607.
Mohd. Razi, Zainul Rashid ; Ong, Fee Bee ; Omar, Mohd Hashim ; Ng, S. P. ; Nurshaireen, A. ; Rahimah, M. D. ; Mariam, S. ; Zolaidah, M. ; Sharifah-Teh, N. S M N ; Saniros, A. ; Hasnita, B. / Predictors of intrauterine insemination success. In: Medical Journal of Malaysia. 2006 ; Vol. 61, No. 5. pp. 599-607.
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