Predicting comorbidities, nutritional status, and neuropsychological performance of depressed and nondepressed geriatric communities

A comparative study

Lai Kuan Lee, Suzana Shahar, Ai Vyrn Chin

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Background: The understanding of the relationship between comorbidities, nutritional status, and cognitive manifestations in depression is limited. This study investigated and compared the association between comorbidity status, nutritional status, and neuropsychological performance in depressed and nondepressed community-dwelling older adults. Methods: This cross-sectional study recruited 318 elderly people aged 60 years and above from 15 low-cost public residential buildings located in the Cheras area, Malaysia. Structured in-person questionnaires were administered to obtain information regarding demographic, socioeconomic, and psychosocial characteristics. The GDS-15 Geriatric Depression Scale was used to measure depressive symptomatology with a threshold of ≤4/≥5. Comorbidity status was confirmed by examination of medical records. Indication of nutritional status included anthropometric measurements, nutritional intake assessments, and biochemical analyses. Comprehensive neuropsychological assessments were conducted to assess cognitive function. All tested parameters were compared with the symptoms of depression. Results: The prevalence of depressive symptoms was 30.2%. Subjects who were lacking habitual exercise were two-fold more likely to have symptoms of depression (adjusted odds ratio: 2.163; 95% confidence interval: 1.236-3.788; p < 0.01). Depressed and nondepressed patients had the same trends in comorbidity status, and no significant differences were noted between the groups on any of the nutritional assessments. However, depressed patients had poorer global cognitive functions (F = 4.740, p < 0.05) and verbal immediate verbal learning and memory (F = 4.113, p < 0.05) compared with the nondepressed patients. Conclusion: This study found that less exercise is an independent predictor of depressive symptomatology. Cognition-enhancing interventions are needed for the at-risk elderly with depressive symptoms in order to prevent the progression to severe depression.

Original languageEnglish
Pages (from-to)278-284
Number of pages7
JournalInternational Journal of Gerontology
Volume6
Issue number4
DOIs
Publication statusPublished - Dec 2012

Fingerprint

Nutritional Status
Geriatrics
Comorbidity
Depression
Cognition
Nutrition Assessment
Exercise
Independent Living
Verbal Learning
Neurobehavioral Manifestations
Malaysia
Medical Records
Cross-Sectional Studies
Odds Ratio
Demography
Confidence Intervals
Costs and Cost Analysis

Keywords

  • cognitive function
  • comorbidity
  • depression
  • nutritional status
  • prevalence

ASJC Scopus subject areas

  • Geriatrics and Gerontology

Cite this

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title = "Predicting comorbidities, nutritional status, and neuropsychological performance of depressed and nondepressed geriatric communities: A comparative study",
abstract = "Background: The understanding of the relationship between comorbidities, nutritional status, and cognitive manifestations in depression is limited. This study investigated and compared the association between comorbidity status, nutritional status, and neuropsychological performance in depressed and nondepressed community-dwelling older adults. Methods: This cross-sectional study recruited 318 elderly people aged 60 years and above from 15 low-cost public residential buildings located in the Cheras area, Malaysia. Structured in-person questionnaires were administered to obtain information regarding demographic, socioeconomic, and psychosocial characteristics. The GDS-15 Geriatric Depression Scale was used to measure depressive symptomatology with a threshold of ≤4/≥5. Comorbidity status was confirmed by examination of medical records. Indication of nutritional status included anthropometric measurements, nutritional intake assessments, and biochemical analyses. Comprehensive neuropsychological assessments were conducted to assess cognitive function. All tested parameters were compared with the symptoms of depression. Results: The prevalence of depressive symptoms was 30.2{\%}. Subjects who were lacking habitual exercise were two-fold more likely to have symptoms of depression (adjusted odds ratio: 2.163; 95{\%} confidence interval: 1.236-3.788; p < 0.01). Depressed and nondepressed patients had the same trends in comorbidity status, and no significant differences were noted between the groups on any of the nutritional assessments. However, depressed patients had poorer global cognitive functions (F = 4.740, p < 0.05) and verbal immediate verbal learning and memory (F = 4.113, p < 0.05) compared with the nondepressed patients. Conclusion: This study found that less exercise is an independent predictor of depressive symptomatology. Cognition-enhancing interventions are needed for the at-risk elderly with depressive symptoms in order to prevent the progression to severe depression.",
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N2 - Background: The understanding of the relationship between comorbidities, nutritional status, and cognitive manifestations in depression is limited. This study investigated and compared the association between comorbidity status, nutritional status, and neuropsychological performance in depressed and nondepressed community-dwelling older adults. Methods: This cross-sectional study recruited 318 elderly people aged 60 years and above from 15 low-cost public residential buildings located in the Cheras area, Malaysia. Structured in-person questionnaires were administered to obtain information regarding demographic, socioeconomic, and psychosocial characteristics. The GDS-15 Geriatric Depression Scale was used to measure depressive symptomatology with a threshold of ≤4/≥5. Comorbidity status was confirmed by examination of medical records. Indication of nutritional status included anthropometric measurements, nutritional intake assessments, and biochemical analyses. Comprehensive neuropsychological assessments were conducted to assess cognitive function. All tested parameters were compared with the symptoms of depression. Results: The prevalence of depressive symptoms was 30.2%. Subjects who were lacking habitual exercise were two-fold more likely to have symptoms of depression (adjusted odds ratio: 2.163; 95% confidence interval: 1.236-3.788; p < 0.01). Depressed and nondepressed patients had the same trends in comorbidity status, and no significant differences were noted between the groups on any of the nutritional assessments. However, depressed patients had poorer global cognitive functions (F = 4.740, p < 0.05) and verbal immediate verbal learning and memory (F = 4.113, p < 0.05) compared with the nondepressed patients. Conclusion: This study found that less exercise is an independent predictor of depressive symptomatology. Cognition-enhancing interventions are needed for the at-risk elderly with depressive symptoms in order to prevent the progression to severe depression.

AB - Background: The understanding of the relationship between comorbidities, nutritional status, and cognitive manifestations in depression is limited. This study investigated and compared the association between comorbidity status, nutritional status, and neuropsychological performance in depressed and nondepressed community-dwelling older adults. Methods: This cross-sectional study recruited 318 elderly people aged 60 years and above from 15 low-cost public residential buildings located in the Cheras area, Malaysia. Structured in-person questionnaires were administered to obtain information regarding demographic, socioeconomic, and psychosocial characteristics. The GDS-15 Geriatric Depression Scale was used to measure depressive symptomatology with a threshold of ≤4/≥5. Comorbidity status was confirmed by examination of medical records. Indication of nutritional status included anthropometric measurements, nutritional intake assessments, and biochemical analyses. Comprehensive neuropsychological assessments were conducted to assess cognitive function. All tested parameters were compared with the symptoms of depression. Results: The prevalence of depressive symptoms was 30.2%. Subjects who were lacking habitual exercise were two-fold more likely to have symptoms of depression (adjusted odds ratio: 2.163; 95% confidence interval: 1.236-3.788; p < 0.01). Depressed and nondepressed patients had the same trends in comorbidity status, and no significant differences were noted between the groups on any of the nutritional assessments. However, depressed patients had poorer global cognitive functions (F = 4.740, p < 0.05) and verbal immediate verbal learning and memory (F = 4.113, p < 0.05) compared with the nondepressed patients. Conclusion: This study found that less exercise is an independent predictor of depressive symptomatology. Cognition-enhancing interventions are needed for the at-risk elderly with depressive symptoms in order to prevent the progression to severe depression.

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