Pre-clinical study on the oral maxillofacial (Omf) titanium alloy implants produced by metal injection molding (Mim) using palm oil based binder system

R. Ibrahim, M. Azmirruddin, M. Jabir, Norhamidi Muhamad, M. Rafiq, N. A. Kasim, S. Muhamad, K. Hanada, T. Shimizu, Y. Itoh

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Metal Injection Molding (MIM) is a cost-effective technique for producing small, complex, precision parts in high volumes. MIM consists of four main processing steps: mixing, injection molding, debinding and sintering. In the mixing step, the powder titanium alloy (Ti6Al4V) medical grade is mixed with a binder system based on palm stearin to form a homogeneous feedstock. The rheological studies of the feedstock have been determined properly in order to success during injection into injection molding machine. After molding, the binder holds the particles in place. The binder systems then have to be removed completely through debinding step. Any contamination of the binder systems will affect the final properties of the implants. During debinding step, solvent extraction debinding has been used to remove partly of the binder systems. The debound implant is then sintered at high temperature under control atmosphere furnace. The physical and mechanical properties of the sintered implants were measured and compared. The sintered implants were also submitted to in-vitro cytotoxicity study using mouse fibroblast lines L-92 and pre-clinical study on a monkey. The results show that the sintered titanium alloy implants produced by MIM fulfill the biocompatibility and pre-clinical test.

Original languageEnglish
Title of host publicationInternational Powder Metallurgy Congress and Exhibition, Euro PM 2013
PublisherEuropean Powder Metallurgy Association (EPMA)
ISBN (Print)9781899072408
Publication statusPublished - 2013
Externally publishedYes
EventInternational Powder Metallurgy Congress and Exhibition, Euro PM 2013 - Gothenburg, Sweden
Duration: 15 Sep 201318 Sep 2013

Other

OtherInternational Powder Metallurgy Congress and Exhibition, Euro PM 2013
CountrySweden
CityGothenburg
Period15/9/1318/9/13

Fingerprint

Metal molding
Palm oil
injection molding
titanium alloys
Titanium alloys
Injection molding
Binders
oils
metals
Feedstocks
monkeys
solvent extraction
fibroblasts
biocompatibility
Solvent extraction
Fibroblasts
Cytotoxicity
Biocompatibility
Molding
Powders

Keywords

  • Binder system
  • Cytotoxicity and pre-clinical
  • Debinding
  • Mixing
  • Powder
  • Sintering

ASJC Scopus subject areas

  • Metals and Alloys
  • Surfaces, Coatings and Films
  • Surfaces and Interfaces

Cite this

Ibrahim, R., Azmirruddin, M., Jabir, M., Muhamad, N., Rafiq, M., Kasim, N. A., ... Itoh, Y. (2013). Pre-clinical study on the oral maxillofacial (Omf) titanium alloy implants produced by metal injection molding (Mim) using palm oil based binder system. In International Powder Metallurgy Congress and Exhibition, Euro PM 2013 European Powder Metallurgy Association (EPMA).

Pre-clinical study on the oral maxillofacial (Omf) titanium alloy implants produced by metal injection molding (Mim) using palm oil based binder system. / Ibrahim, R.; Azmirruddin, M.; Jabir, M.; Muhamad, Norhamidi; Rafiq, M.; Kasim, N. A.; Muhamad, S.; Hanada, K.; Shimizu, T.; Itoh, Y.

International Powder Metallurgy Congress and Exhibition, Euro PM 2013. European Powder Metallurgy Association (EPMA), 2013.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Ibrahim, R, Azmirruddin, M, Jabir, M, Muhamad, N, Rafiq, M, Kasim, NA, Muhamad, S, Hanada, K, Shimizu, T & Itoh, Y 2013, Pre-clinical study on the oral maxillofacial (Omf) titanium alloy implants produced by metal injection molding (Mim) using palm oil based binder system. in International Powder Metallurgy Congress and Exhibition, Euro PM 2013. European Powder Metallurgy Association (EPMA), International Powder Metallurgy Congress and Exhibition, Euro PM 2013, Gothenburg, Sweden, 15/9/13.
Ibrahim R, Azmirruddin M, Jabir M, Muhamad N, Rafiq M, Kasim NA et al. Pre-clinical study on the oral maxillofacial (Omf) titanium alloy implants produced by metal injection molding (Mim) using palm oil based binder system. In International Powder Metallurgy Congress and Exhibition, Euro PM 2013. European Powder Metallurgy Association (EPMA). 2013
Ibrahim, R. ; Azmirruddin, M. ; Jabir, M. ; Muhamad, Norhamidi ; Rafiq, M. ; Kasim, N. A. ; Muhamad, S. ; Hanada, K. ; Shimizu, T. ; Itoh, Y. / Pre-clinical study on the oral maxillofacial (Omf) titanium alloy implants produced by metal injection molding (Mim) using palm oil based binder system. International Powder Metallurgy Congress and Exhibition, Euro PM 2013. European Powder Metallurgy Association (EPMA), 2013.
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