Pre and post PET-CT impact on oesophageal cancer management: A retrospective analysis

Nor Aniza Azmi, H. R.A. Razak, S. Vinjamuri

Research output: Contribution to journalConference article

Abstract

Assessment of the retrospective cancer incidence, prevalence and crude survival rates of oesophageal cancer to allow comparison between pre and post PET-CT introduction are part of 4 phase cost effectiveness research. It will provide baseline data for to assess PET or PET-CT cost effective potential for staging. A total of 849 patient's data received from NWCIS databases with various stages of oesophageal cancer between 2001 and 2008. The fundamental activities are retrospective analysis of patient data. In most cases where appropriate, results are presented with 95 percent confidence intervals (CI). Variances between patient groups and variables are assessed using chi-square test. In cases where it deems vital, multiple logistic regression are used to modify for potential confounder such as age and sex. All p-values are two-sided and any value lower than 0.05 were considered to suggest a statistically significant result. Retrospective analysis were categorised into two categories, patients from 2001-2003 considered as pre PET and post PET for 2004-2008. This categorisation allows better comparison of patients' survival trend to be made between both groups. Rates are presented in percentages and being grouped by tumour characteristics and other variables associated with demographic profile, diagnosis, staging and treatment. Results allowed comparison of oesophageal cancer trends between the pre and post PET-CT introduction such as changes in incidence rate or changes in survival. These data were used to normalise the decision tree model so that cost-effectiveness analysis can be performed across the whole population.

Original languageEnglish
Article number012040
JournalJournal of Physics: Conference Series
Volume851
Issue number1
DOIs
Publication statusPublished - 31 May 2017
Event10th International Seminar on Medical Physics, ISMP 2016 and 1st AMDI International Oncology Symposium, IOS 2016 - Penang, Malaysia
Duration: 26 Aug 201628 Aug 2016

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cancer
cost effectiveness
incidence
trends
logistics
regression analysis
confidence
tumors
costs
intervals
profiles

ASJC Scopus subject areas

  • Physics and Astronomy(all)

Cite this

Pre and post PET-CT impact on oesophageal cancer management : A retrospective analysis. / Azmi, Nor Aniza; Razak, H. R.A.; Vinjamuri, S.

In: Journal of Physics: Conference Series, Vol. 851, No. 1, 012040, 31.05.2017.

Research output: Contribution to journalConference article

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