Pre-ablative diagnostic whole-body scan following total thyroidectomy for well-differentiated thyroid cancer: Is it necessary?

Choon Meng Teoh, Rohaizak Muhammad, Kin Yoong Chan, Ali Yaakub Jasmi, Fuad Ismail

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

OBJECTIVE: This study reviewed the incidence of positive pre-ablative diagnostic scan after total thyroidectomy and the efficacy of the current ablative dose. The predictive factors for outcome using a standard ablative dose and postoperative complications of total thyroidectomy were also examined. METHODS: This was a retrospective review of patients referred for radioiodine ablation after total thyroidectomy between September 1997 and September 2001. RESULTS: Forty patients were included in this study, of whom 95% had a positive scan after total thyroidectomy. Of the 30 patients who underwent standard 80-mCi radioiodine ablation, 21 (70%) had successful single ablation while the remaining nine patients needed a higher ablative dose. There were no significant differences between patients who had successful ablation with the standard dose and those who did not in terms of tumour size, patient age, lymph node status and extra-thyroidal extension. Fifteen percent suffered from permanent hypoparathyroidism requiring calcium supplementation. Three patients had documented recurrent laryngeal nerve paralysis. CONCLUSION: Bypassing the pre-ablative diagnostic scan is feasible. The present ablation dose of 80 mCi of radioiodine is effective. The relatively high postoperative morbidity after difficult total thyroidectomy suggests less aggressive excision and postoperative radioiodine ablation of the remnant tissue.

Original languageEnglish
Pages (from-to)90-96
Number of pages7
JournalAsian Journal of Surgery
Volume28
Issue number2
Publication statusPublished - Apr 2005

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Whole Body Imaging
Thyroidectomy
Thyroid Neoplasms
Recurrent Laryngeal Nerve
Vocal Cord Paralysis
Hypoparathyroidism
Cohort Studies
Lymph Nodes
Calcium
Morbidity

Keywords

  • Radioiodine ablation
  • Recurrent laryngeal nerve
  • Thyroid carcinoma
  • Total thyroidectomy

ASJC Scopus subject areas

  • Surgery

Cite this

Pre-ablative diagnostic whole-body scan following total thyroidectomy for well-differentiated thyroid cancer : Is it necessary? / Teoh, Choon Meng; Muhammad, Rohaizak; Chan, Kin Yoong; Jasmi, Ali Yaakub; Ismail, Fuad.

In: Asian Journal of Surgery, Vol. 28, No. 2, 04.2005, p. 90-96.

Research output: Contribution to journalArticle

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