Popcorn-like calcification in the breast

More than meets the eye?

Norlia Abdullah, Radhika Sridharan, A. Saeid, I. M. Rose, Z. M. Annuar

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

We present a case of a 56-year-old woman who had mammographie findings of coarse popcorn-like calcification in the right breast. In year 2000, the patient had benign lumps in both breasts, which were excised. Subsequent ultrasound examination revealed a 0.7 cm × 0.4 cm hypoechoic nodule. The lesion displayed irregular superficial margin and thus was assigned Breast Imaging Reporting and Data System category 4 with a decision to proceed with a biopsy. Core needle biopsy and histopathology showed involuting fibroadenoma without evidence of malignancy. In view of the discordant results, subsequent excision was performed which confirmed osseous metaplasia. This case report aimed to describe a relatively rare occurrence of mammary osseous metaplasia arising from an involuting fibroadenoma. Coarse popcorn-like calcifications on mammogram are commonly thought to be invariably benign and are therefore not subjected to further imaging or follow-up. What is not commonly known, however, is the fact that these calcifications can progress to osseous metaplasia as demonstrated in this patient. Literature reviews have shown a few cases of mammary osseous metaplasia that transformed into osteosarcoma. Therefore, this case deserves to be highlighted to radiologists and surgeons alike that mammographically detected coarse popcorn-like calcification in the breast could in fact represent osseous metaplasia. Henceforth, such cases warrant a more thorough evaluation, and possibly excision with histopathological evaluation to exclude sarcomatous transformation.

Original languageEnglish
Pages (from-to)152-155
Number of pages4
JournalHong Kong Journal of Radiology
Volume18
Issue number2
DOIs
Publication statusPublished - 1 Jun 2015

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Metaplasia
Breast
Fibroadenoma
Large-Core Needle Biopsy
Osteosarcoma
Information Systems
Biopsy
Neoplasms

Keywords

  • Breast diseases
  • Fibroadenoma
  • Heterotopic
  • Metaplasia
  • Ossification

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Cite this

Popcorn-like calcification in the breast : More than meets the eye? / Abdullah, Norlia; Sridharan, Radhika; Saeid, A.; Rose, I. M.; Annuar, Z. M.

In: Hong Kong Journal of Radiology, Vol. 18, No. 2, 01.06.2015, p. 152-155.

Research output: Contribution to journalArticle

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