Polypharmacy and Willingness to Deprescribe Among Elderly with Chronic Diseases

Research output: Contribution to journalArticle

Abstract

Background: Elderly are mostly affected by polypharmacy induced adverse drug events as they are vulnerable due to numerous comorbidities. Deprescribing is a series of medicine ceasing process introduced to solve the problem arisen from polypharmacy. This study aimed to investigate the attitudes, beliefs and experiences towards polypharmacy among elderly with chronic diseases and their willingness to be deprescribed. Methods: A cross-sectional study was conducted among elderly patients in a tertiary hospital in Malaysia from August 2017 to October 2017 using a researcher assisted and validated questionnaire. Results: A total number of 222 elderly patients were included in this study. 45.5% (n = 101) of the participants agreed that they were taking a large number of medicines (95% CI = 38.89%–52.10%). 56.3% (n = 125) of the participants had the desire to reduce their number of medications (95% CI = 49.73%–62.88%). Majority of them (n = 185, 83.33%) agreed to involve themselves in deprescribing process if permitted by their health care provider. 86.9% (n = 193) of the participants tended to not be afraid of deprescribing of their regular medications after a series of investigations by their health care provider (95% CI = 81%–89%). Conclusion: Majority of the elderly would like to participate in deprescribing process. Major factors that will affect patients' willingness to deprescribe were physicians' time and support as well as possible future benefits of their regular medications.

Original languageEnglish
JournalInternational Journal of Gerontology
DOIs
Publication statusAccepted/In press - 1 Jan 2018

Fingerprint

Polypharmacy
Chronic Disease
Health Personnel
Malaysia
Drug-Related Side Effects and Adverse Reactions
Tertiary Care Centers
Comorbidity
Cross-Sectional Studies
Research Personnel
Medicine
Physicians
Deprescriptions

Keywords

  • aged
  • chronic disease
  • medication
  • polypharmacy

ASJC Scopus subject areas

  • Geriatrics and Gerontology

Cite this

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title = "Polypharmacy and Willingness to Deprescribe Among Elderly with Chronic Diseases",
abstract = "Background: Elderly are mostly affected by polypharmacy induced adverse drug events as they are vulnerable due to numerous comorbidities. Deprescribing is a series of medicine ceasing process introduced to solve the problem arisen from polypharmacy. This study aimed to investigate the attitudes, beliefs and experiences towards polypharmacy among elderly with chronic diseases and their willingness to be deprescribed. Methods: A cross-sectional study was conducted among elderly patients in a tertiary hospital in Malaysia from August 2017 to October 2017 using a researcher assisted and validated questionnaire. Results: A total number of 222 elderly patients were included in this study. 45.5{\%} (n = 101) of the participants agreed that they were taking a large number of medicines (95{\%} CI = 38.89{\%}–52.10{\%}). 56.3{\%} (n = 125) of the participants had the desire to reduce their number of medications (95{\%} CI = 49.73{\%}–62.88{\%}). Majority of them (n = 185, 83.33{\%}) agreed to involve themselves in deprescribing process if permitted by their health care provider. 86.9{\%} (n = 193) of the participants tended to not be afraid of deprescribing of their regular medications after a series of investigations by their health care provider (95{\%} CI = 81{\%}–89{\%}). Conclusion: Majority of the elderly would like to participate in deprescribing process. Major factors that will affect patients' willingness to deprescribe were physicians' time and support as well as possible future benefits of their regular medications.",
keywords = "aged, chronic disease, medication, polypharmacy",
author = "{Jia Hao}, Lim and Omar, {Marhanis Salihah} and {Mohd Tohit @ Mohd Tauhid}, Noorlaili",
year = "2018",
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doi = "10.1016/j.ijge.2018.05.006",
language = "English",
journal = "International Journal of Gerontology",
issn = "1873-9598",
publisher = "Elsevier Taiwan LLC",

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AU - Jia Hao, Lim

AU - Omar, Marhanis Salihah

AU - Mohd Tohit @ Mohd Tauhid, Noorlaili

PY - 2018/1/1

Y1 - 2018/1/1

N2 - Background: Elderly are mostly affected by polypharmacy induced adverse drug events as they are vulnerable due to numerous comorbidities. Deprescribing is a series of medicine ceasing process introduced to solve the problem arisen from polypharmacy. This study aimed to investigate the attitudes, beliefs and experiences towards polypharmacy among elderly with chronic diseases and their willingness to be deprescribed. Methods: A cross-sectional study was conducted among elderly patients in a tertiary hospital in Malaysia from August 2017 to October 2017 using a researcher assisted and validated questionnaire. Results: A total number of 222 elderly patients were included in this study. 45.5% (n = 101) of the participants agreed that they were taking a large number of medicines (95% CI = 38.89%–52.10%). 56.3% (n = 125) of the participants had the desire to reduce their number of medications (95% CI = 49.73%–62.88%). Majority of them (n = 185, 83.33%) agreed to involve themselves in deprescribing process if permitted by their health care provider. 86.9% (n = 193) of the participants tended to not be afraid of deprescribing of their regular medications after a series of investigations by their health care provider (95% CI = 81%–89%). Conclusion: Majority of the elderly would like to participate in deprescribing process. Major factors that will affect patients' willingness to deprescribe were physicians' time and support as well as possible future benefits of their regular medications.

AB - Background: Elderly are mostly affected by polypharmacy induced adverse drug events as they are vulnerable due to numerous comorbidities. Deprescribing is a series of medicine ceasing process introduced to solve the problem arisen from polypharmacy. This study aimed to investigate the attitudes, beliefs and experiences towards polypharmacy among elderly with chronic diseases and their willingness to be deprescribed. Methods: A cross-sectional study was conducted among elderly patients in a tertiary hospital in Malaysia from August 2017 to October 2017 using a researcher assisted and validated questionnaire. Results: A total number of 222 elderly patients were included in this study. 45.5% (n = 101) of the participants agreed that they were taking a large number of medicines (95% CI = 38.89%–52.10%). 56.3% (n = 125) of the participants had the desire to reduce their number of medications (95% CI = 49.73%–62.88%). Majority of them (n = 185, 83.33%) agreed to involve themselves in deprescribing process if permitted by their health care provider. 86.9% (n = 193) of the participants tended to not be afraid of deprescribing of their regular medications after a series of investigations by their health care provider (95% CI = 81%–89%). Conclusion: Majority of the elderly would like to participate in deprescribing process. Major factors that will affect patients' willingness to deprescribe were physicians' time and support as well as possible future benefits of their regular medications.

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