Polydimethlsiloxane (PDMS) microchannel with trapping chamber for BioMEMS applications

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

This study presents fabrication and simulation of a microchannel for BioMEMS applications. The basic construction of this microfluidics channel consists of an inlet and an outlet, a microchannel for transporting continuous fluid flow and a trapping chamber as mean of trapping and separating the intended biological cells. The microchannel is constructed using polydimethlsiloxane (PDMS) using replica molding technique from SU-8 mold. The flow characteristics and the pressure drop experienced by microchannel have been modeled and simulated using Finite Element Analysis (FEA). The simulation results revealed a linear relationship of velocity magnitude and pressure drop with volumetric flow rate in the range of 0.5 to 1000 μL/min. Furthermore, the velocity streamlines indicated a laminar fluid characteristic is maintained in the microchannel flow at maximum volumetric flow rate of 1000 μL/min. Pressure drop is a vital parameter in a microchannel design due to the bonding limit between the PDMS microchannel and its substrate. In this work, a maximum pressure drop of 14.8 kPa is developed at maximum volumetric flow rate of 1000 μL/min. The pressure drop is in a safe limit for PDMS microchannel bonded with PDMS layer substrate operation.

Original languageEnglish
Title of host publicationIEEE International Conference on Semiconductor Electronics, Proceedings, ICSE
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages270-273
Number of pages4
ISBN (Print)9781479957606
DOIs
Publication statusPublished - 10 Oct 2014
Event11th IEEE International Conference on Semiconductor Electronics, ICSE 2014 - Kuala Lumpur
Duration: 27 Aug 201429 Aug 2014

Other

Other11th IEEE International Conference on Semiconductor Electronics, ICSE 2014
CityKuala Lumpur
Period27/8/1429/8/14

Fingerprint

BioMEMS
Microchannels
Pressure drop
Flow rate
Substrates
Microfluidics
Molding
Flow of fluids
Finite element method
Fabrication

Keywords

  • BioMEMS
  • Finite Element Analysis (FEA)
  • microchannel
  • microfluidics
  • polydimethylsiloxane (PDMS)

ASJC Scopus subject areas

  • Electrical and Electronic Engineering
  • Electronic, Optical and Magnetic Materials

Cite this

Abidin, U., Yeop Majlis, B., & Yunas, J. (2014). Polydimethlsiloxane (PDMS) microchannel with trapping chamber for BioMEMS applications. In IEEE International Conference on Semiconductor Electronics, Proceedings, ICSE (pp. 270-273). [6920849] Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/SMELEC.2014.6920849

Polydimethlsiloxane (PDMS) microchannel with trapping chamber for BioMEMS applications. / Abidin, Ummikalsom; Yeop Majlis, Burhanuddin; Yunas, Jumril.

IEEE International Conference on Semiconductor Electronics, Proceedings, ICSE. Institute of Electrical and Electronics Engineers Inc., 2014. p. 270-273 6920849.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abidin, U, Yeop Majlis, B & Yunas, J 2014, Polydimethlsiloxane (PDMS) microchannel with trapping chamber for BioMEMS applications. in IEEE International Conference on Semiconductor Electronics, Proceedings, ICSE., 6920849, Institute of Electrical and Electronics Engineers Inc., pp. 270-273, 11th IEEE International Conference on Semiconductor Electronics, ICSE 2014, Kuala Lumpur, 27/8/14. https://doi.org/10.1109/SMELEC.2014.6920849
Abidin U, Yeop Majlis B, Yunas J. Polydimethlsiloxane (PDMS) microchannel with trapping chamber for BioMEMS applications. In IEEE International Conference on Semiconductor Electronics, Proceedings, ICSE. Institute of Electrical and Electronics Engineers Inc. 2014. p. 270-273. 6920849 https://doi.org/10.1109/SMELEC.2014.6920849
Abidin, Ummikalsom ; Yeop Majlis, Burhanuddin ; Yunas, Jumril. / Polydimethlsiloxane (PDMS) microchannel with trapping chamber for BioMEMS applications. IEEE International Conference on Semiconductor Electronics, Proceedings, ICSE. Institute of Electrical and Electronics Engineers Inc., 2014. pp. 270-273
@inproceedings{cfdd65bf95ea4124ae2a790ab83f4d68,
title = "Polydimethlsiloxane (PDMS) microchannel with trapping chamber for BioMEMS applications",
abstract = "This study presents fabrication and simulation of a microchannel for BioMEMS applications. The basic construction of this microfluidics channel consists of an inlet and an outlet, a microchannel for transporting continuous fluid flow and a trapping chamber as mean of trapping and separating the intended biological cells. The microchannel is constructed using polydimethlsiloxane (PDMS) using replica molding technique from SU-8 mold. The flow characteristics and the pressure drop experienced by microchannel have been modeled and simulated using Finite Element Analysis (FEA). The simulation results revealed a linear relationship of velocity magnitude and pressure drop with volumetric flow rate in the range of 0.5 to 1000 μL/min. Furthermore, the velocity streamlines indicated a laminar fluid characteristic is maintained in the microchannel flow at maximum volumetric flow rate of 1000 μL/min. Pressure drop is a vital parameter in a microchannel design due to the bonding limit between the PDMS microchannel and its substrate. In this work, a maximum pressure drop of 14.8 kPa is developed at maximum volumetric flow rate of 1000 μL/min. The pressure drop is in a safe limit for PDMS microchannel bonded with PDMS layer substrate operation.",
keywords = "BioMEMS, Finite Element Analysis (FEA), microchannel, microfluidics, polydimethylsiloxane (PDMS)",
author = "Ummikalsom Abidin and {Yeop Majlis}, Burhanuddin and Jumril Yunas",
year = "2014",
month = "10",
day = "10",
doi = "10.1109/SMELEC.2014.6920849",
language = "English",
isbn = "9781479957606",
pages = "270--273",
booktitle = "IEEE International Conference on Semiconductor Electronics, Proceedings, ICSE",
publisher = "Institute of Electrical and Electronics Engineers Inc.",

}

TY - GEN

T1 - Polydimethlsiloxane (PDMS) microchannel with trapping chamber for BioMEMS applications

AU - Abidin, Ummikalsom

AU - Yeop Majlis, Burhanuddin

AU - Yunas, Jumril

PY - 2014/10/10

Y1 - 2014/10/10

N2 - This study presents fabrication and simulation of a microchannel for BioMEMS applications. The basic construction of this microfluidics channel consists of an inlet and an outlet, a microchannel for transporting continuous fluid flow and a trapping chamber as mean of trapping and separating the intended biological cells. The microchannel is constructed using polydimethlsiloxane (PDMS) using replica molding technique from SU-8 mold. The flow characteristics and the pressure drop experienced by microchannel have been modeled and simulated using Finite Element Analysis (FEA). The simulation results revealed a linear relationship of velocity magnitude and pressure drop with volumetric flow rate in the range of 0.5 to 1000 μL/min. Furthermore, the velocity streamlines indicated a laminar fluid characteristic is maintained in the microchannel flow at maximum volumetric flow rate of 1000 μL/min. Pressure drop is a vital parameter in a microchannel design due to the bonding limit between the PDMS microchannel and its substrate. In this work, a maximum pressure drop of 14.8 kPa is developed at maximum volumetric flow rate of 1000 μL/min. The pressure drop is in a safe limit for PDMS microchannel bonded with PDMS layer substrate operation.

AB - This study presents fabrication and simulation of a microchannel for BioMEMS applications. The basic construction of this microfluidics channel consists of an inlet and an outlet, a microchannel for transporting continuous fluid flow and a trapping chamber as mean of trapping and separating the intended biological cells. The microchannel is constructed using polydimethlsiloxane (PDMS) using replica molding technique from SU-8 mold. The flow characteristics and the pressure drop experienced by microchannel have been modeled and simulated using Finite Element Analysis (FEA). The simulation results revealed a linear relationship of velocity magnitude and pressure drop with volumetric flow rate in the range of 0.5 to 1000 μL/min. Furthermore, the velocity streamlines indicated a laminar fluid characteristic is maintained in the microchannel flow at maximum volumetric flow rate of 1000 μL/min. Pressure drop is a vital parameter in a microchannel design due to the bonding limit between the PDMS microchannel and its substrate. In this work, a maximum pressure drop of 14.8 kPa is developed at maximum volumetric flow rate of 1000 μL/min. The pressure drop is in a safe limit for PDMS microchannel bonded with PDMS layer substrate operation.

KW - BioMEMS

KW - Finite Element Analysis (FEA)

KW - microchannel

KW - microfluidics

KW - polydimethylsiloxane (PDMS)

UR - http://www.scopus.com/inward/record.url?scp=84908238842&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84908238842&partnerID=8YFLogxK

U2 - 10.1109/SMELEC.2014.6920849

DO - 10.1109/SMELEC.2014.6920849

M3 - Conference contribution

SN - 9781479957606

SP - 270

EP - 273

BT - IEEE International Conference on Semiconductor Electronics, Proceedings, ICSE

PB - Institute of Electrical and Electronics Engineers Inc.

ER -