Plasma BNP level as marker for early detection of heart failure in primary hypertensive patients

J. Norsham, S. M. Azmani, H. Roslan, M. A. Latiff

    Research output: Contribution to journalArticle

    Abstract

    Heart failure is chiefly the end stage of primary hypertension and a major public health problem in Malaysia. The aim of this work is to investigate the level of BNP that may discriminate between primary hypertension patients without heart failure and primary hypertensive patients with heart failure. This study was conducted on 60 hypertensive patients without any clinical symptoms of heart failure referred for echocardiography to evaluate the ventricular function. Patients with metabolic diseases and terminal diseases were excluded from the study. The BNP levels were assessed using the Triage Meter from Biosite Diagnostics. Results showed that BNP level display a negative correlation with ejection fraction (Pearson correlation test). The significant result (paired t test, p < 0.05) proves that both predictors are very important and relates to each other. Low ejection fraction is significantly marked with raised BNP level suggesting that BNP may play potential role as screening tool for early detection of heart failure in primary hypertensive patients.

    Original languageEnglish
    Pages (from-to)13-19
    Number of pages7
    JournalMalaysian Journal of Medicine and Health Sciences
    Volume8
    Issue number1
    Publication statusPublished - Jan 2012

    Fingerprint

    Heart Failure
    Hypertension
    Ventricular Function
    Triage
    Malaysia
    Metabolic Diseases
    Echocardiography
    Public Health

    Keywords

    • BNP
    • Heart failure
    • Hypertension

    ASJC Scopus subject areas

    • Medicine(all)

    Cite this

    Plasma BNP level as marker for early detection of heart failure in primary hypertensive patients. / Norsham, J.; Azmani, S. M.; Roslan, H.; Latiff, M. A.

    In: Malaysian Journal of Medicine and Health Sciences, Vol. 8, No. 1, 01.2012, p. 13-19.

    Research output: Contribution to journalArticle

    Norsham, J. ; Azmani, S. M. ; Roslan, H. ; Latiff, M. A. / Plasma BNP level as marker for early detection of heart failure in primary hypertensive patients. In: Malaysian Journal of Medicine and Health Sciences. 2012 ; Vol. 8, No. 1. pp. 13-19.
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