Phytochemistry, cytotoxicity and antiviral activity of Eleusine indica (sambau)

Rashidah Iberahim, Wan Yaacob Wan Ahmad, Nazlina Ibrahim

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Citations (Scopus)

Abstract

Goose grass also known as Eleusine indica (EI) is a local medicinal plant that displays antioxidant, antimicrobial and anticancer activities. The present study is to determine the phytochemical constituents, cytotoxicity and antiviral activities for both crude extract and fraction obtained from the plant. The crude extract contained more secondary metabolites compared to the hexane fraction as gauged using standard phytochemical tests. Cytotoxicity screening against Vero cells using MTT assay showed that the CC50 values for crude extract and hexane fraction were 2.07 and 5.62 mg/ml respectively. The antiviral activity towards Herpes Simplex Virus type 1 (HSV-1) was determined using plaque reduction assay. The selective indices (SI = CC50 / EC50) for both methanol extract and hexane fraction were 12.2 and 6.2 respectively. These results demonstrate that the extract prepared from E. indica possesses phytochemical compound that was non cytotoxic to the cell with potential antiviral activity.

Original languageEnglish
Title of host publication2015 UKM FST Postgraduate Colloquium: Proceedings of the Universiti Kebangsaan Malaysia, Faculty of Science and Technology 2015 Postgraduate Colloquium
PublisherAmerican Institute of Physics Inc.
Volume1678
ISBN (Electronic)9780735413252
DOIs
Publication statusPublished - 25 Sep 2015
Event2015 Postgraduate Colloquium of the Universiti Kebangsaan Malaysia, Faculty of Science and Technology, UKM FST 2015 - Selangor, Malaysia
Duration: 15 Apr 201516 Apr 2015

Other

Other2015 Postgraduate Colloquium of the Universiti Kebangsaan Malaysia, Faculty of Science and Technology, UKM FST 2015
CountryMalaysia
CitySelangor
Period15/4/1516/4/15

Fingerprint

grasses
metabolites
International System of Units
antioxidants
viruses
cells
screening
methyl alcohol

ASJC Scopus subject areas

  • Physics and Astronomy(all)

Cite this

Iberahim, R., Wan Ahmad, W. Y., & Ibrahim, N. (2015). Phytochemistry, cytotoxicity and antiviral activity of Eleusine indica (sambau). In 2015 UKM FST Postgraduate Colloquium: Proceedings of the Universiti Kebangsaan Malaysia, Faculty of Science and Technology 2015 Postgraduate Colloquium (Vol. 1678). [030013] American Institute of Physics Inc.. https://doi.org/10.1063/1.4931234

Phytochemistry, cytotoxicity and antiviral activity of Eleusine indica (sambau). / Iberahim, Rashidah; Wan Ahmad, Wan Yaacob; Ibrahim, Nazlina.

2015 UKM FST Postgraduate Colloquium: Proceedings of the Universiti Kebangsaan Malaysia, Faculty of Science and Technology 2015 Postgraduate Colloquium. Vol. 1678 American Institute of Physics Inc., 2015. 030013.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Iberahim, R, Wan Ahmad, WY & Ibrahim, N 2015, Phytochemistry, cytotoxicity and antiviral activity of Eleusine indica (sambau). in 2015 UKM FST Postgraduate Colloquium: Proceedings of the Universiti Kebangsaan Malaysia, Faculty of Science and Technology 2015 Postgraduate Colloquium. vol. 1678, 030013, American Institute of Physics Inc., 2015 Postgraduate Colloquium of the Universiti Kebangsaan Malaysia, Faculty of Science and Technology, UKM FST 2015, Selangor, Malaysia, 15/4/15. https://doi.org/10.1063/1.4931234
Iberahim R, Wan Ahmad WY, Ibrahim N. Phytochemistry, cytotoxicity and antiviral activity of Eleusine indica (sambau). In 2015 UKM FST Postgraduate Colloquium: Proceedings of the Universiti Kebangsaan Malaysia, Faculty of Science and Technology 2015 Postgraduate Colloquium. Vol. 1678. American Institute of Physics Inc. 2015. 030013 https://doi.org/10.1063/1.4931234
Iberahim, Rashidah ; Wan Ahmad, Wan Yaacob ; Ibrahim, Nazlina. / Phytochemistry, cytotoxicity and antiviral activity of Eleusine indica (sambau). 2015 UKM FST Postgraduate Colloquium: Proceedings of the Universiti Kebangsaan Malaysia, Faculty of Science and Technology 2015 Postgraduate Colloquium. Vol. 1678 American Institute of Physics Inc., 2015.
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