Phytochemistry and antibacterial activity of cynometra cauliflora

Noor Zarina Abd Wahab, Norhidayah Badya, Nazlina Ibrahim, Mohd Khairul Amri Kamarudin

Research output: Contribution to journalArticle

Abstract

Here we report the potential of Cynometra cauliflora methanolic leaves extract as potential antibacterial agent against clinical isolated microorganisms. Phytochemical analyses reveal the presence of tannin, flavonoid, saponins, cardiac glycosides and terpenoids. In spot test, antibacterial activity can be observed through the formation of zone inhibition of three types of bacteria only which are at concentration of extract used were 75 mg/mL and 100 mg/mL. The MIC was determined ranging from 6.25 mg/mL to 100 mg/mL. The highest value of MIC showed by MRSA which is 6.25 mg/mL. For MBC test, no antibacterial activity have been observed showed that the extract was bacteriostatic which can inhibit the growth of bacteria at concentration less than 100 mg/mL but not kill the bacteria. The results provide evidence that leaves of C. cauliflora extract might indeed be used as a potential source of effective natural antimicrobial agents in pharmaceutical industries. Our findings suggest that C. cauliflora methanolic leaves extract contains antibacterial active compounds and could be potential antibacterial agent.

Original languageEnglish
Pages (from-to)765-769
Number of pages5
JournalIndian Journal of Public Health Research and Development
Volume10
Issue number4
DOIs
Publication statusPublished - 1 Apr 2019

Fingerprint

Bacteria
Anti-Bacterial Agents
Cardiac Glycosides
Tannins
Terpenes
Saponins
Drug Industry
Phytochemicals
Methicillin-Resistant Staphylococcus aureus
Anti-Infective Agents
Flavonoids
Growth

Keywords

  • Antibacterial
  • Cynometra cauliflora
  • Cytotoxicity
  • Phytochemistry

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health

Cite this

Phytochemistry and antibacterial activity of cynometra cauliflora. / Wahab, Noor Zarina Abd; Badya, Norhidayah; Ibrahim, Nazlina; Kamarudin, Mohd Khairul Amri.

In: Indian Journal of Public Health Research and Development, Vol. 10, No. 4, 01.04.2019, p. 765-769.

Research output: Contribution to journalArticle

Wahab, Noor Zarina Abd ; Badya, Norhidayah ; Ibrahim, Nazlina ; Kamarudin, Mohd Khairul Amri. / Phytochemistry and antibacterial activity of cynometra cauliflora. In: Indian Journal of Public Health Research and Development. 2019 ; Vol. 10, No. 4. pp. 765-769.
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